Automated access to well-defined ionic oligosaccharides

Zhu, Yuntao; Tyrikos-Ergas, Theodore; Schiefelbein, Kevin; Grafmüller, Andrea; Seeberger, Peter H.; Delbianco, Martina

doi:10.1039/D0OB00137F

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学術論文

Automated access to well-defined ionic oligosaccharides

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Zhu, Yuntao
Peter H. Seeberger - Automated Systems, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons227007

Tyrikos-Ergas, Theodore
Martina Delbianco, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

Schiefelbein, Kevin
Peter H. Seeberger - Automated Systems, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons121351

Grafmüller, Andrea
Andrea Grafmüller, Theorie & Bio-Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Seeberger, Peter H.
Peter H. Seeberger - Automated Systems, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

/persons/resource/persons187996

Delbianco, Martina
Martina Delbianco, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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引用

Zhu, Y., Tyrikos-Ergas, T., Schiefelbein, K., Grafmüller, A., Seeberger, P. H., & Delbianco, M. (2020). Automated access to well-defined ionic oligosaccharides. Organic & Biomolecular Chemistry, 18(7), 1349-1353. doi:10.1039/D0OB00137F.

引用: https://hdl.handle.net/21.11116/0000-0005-9A91-9

要旨

Ionic polysaccharides are part of many biological events, but lack structural characterisation due to challenging purifications and complex synthesis. Four monosaccharides bearing modifications not found in nature are used for the automated synthesis of a collection of ionic oligosaccharides. Structural analysis reveals how the charge pattern affects glycan conformation.