Appetite for Arginine: Metabolic Control of Macrophage Hunger

Puleston, Daniel; Pearce, Erika L.

doi:10.1016/j.cmet.2020.02.005

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Appetite for Arginine: Metabolic Control of Macrophage Hunger

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Puleston, Daniel
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Pearce, Erika L.
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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https://www.sciencedirect.com/science/article/abs/pii/S1550413120300644?via%3Dihub
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Citation

Puleston, D., & Pearce, E. L. (2020). Appetite for Arginine: Metabolic Control of Macrophage Hunger. Cell Metabolism, 31, 441-442. doi:10.1016/j.cmet.2020.02.005.

Cite as: https://hdl.handle.net/21.11116/0000-0006-3B82-5

Abstract

Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.