Antibacterial and degradable thioimidazolium poly(ionic liquid)

Smith, Christene A.; Cataldo, Vincenzo Alessandro; Dimke, Thomas; Stephan, Ina; Guterman, Ryan

doi:10.1021/acssuschemeng.0c02666

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Antibacterial and degradable thioimidazolium poly(ionic liquid)

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Smith, Christene A.
Ryan Guterman, Kolloidchemie, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Cataldo, Vincenzo Alessandro
Ryan Guterman, Kolloidchemie, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Guterman, Ryan
Ryan Guterman, Kolloidchemie, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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引用

Smith, C. A., Cataldo, V. A., Dimke, T., Stephan, I., & Guterman, R. (2020). Antibacterial and degradable thioimidazolium poly(ionic liquid). ACS Sustainable Chemistry & Engineering, 8(22), 8419-8424. doi:10.1021/acssuschemeng.0c02666.

引用: https://hdl.handle.net/21.11116/0000-0006-6D31-9

要旨

New antibacterial agents are urgently required to fight the emergence of antibiotic-resistant bacteria. We recently synthesized the first thioimidazolium ionene, which has antibacterial properties and can degrade in various media. This dual functionality is crucial in order to limit the environmental impact of these biocides. We have found that our polymer is stronger than benzalkonium chloride (BAC) against Pseudomonas aeruginosa and also readily degrades in the presence of base, while remaining stable in acidic environments. These results highlight a new emerging class of antibacterial degradable polymers.