date: 2020-07-28T06:09:41Z
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pdf:docinfo:title: Impact of Surface Chemistry and Doping Concentrations on Biofunctionalization of GaN/Ga-In-N Quantum Wells
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subject: The development of sensitive biosensors, such as gallium nitride (GaN)-based quantum wells, transistors, etc., often makes it necessary to functionalize GaN surfaces with small molecules or eVen biomolecules, such as proteins. As a first step in surface functionalization, we have investigated silane adsorption, as well as the formation of very thin silane layers. In the next step, the immobilization of the tetrameric protein streptavidin (as well as the attachment of chemically modified iron transport protein ferritin (ferritin-biotin-rhodamine complex)) was realized on these films. The degree of functionalization of the GaN surfaces was determined by fluorescence measurements with fluorescent-labeled proteins; silane film thickness and surface roughness were estimated, and also other surface sensitive techniques were applied. The formation of a monolayer consisting of adsorbed organosilanes was accomplished on Mg-doped GaN surfaces, and also functionalization with proteins was achieved. We found that very high Mg doping reduced the amount of surface functionalized proteins. Most likely, this finding was a consequence of the lower concentration of ionizable Mg atoms in highly Mg-doped layers as a consequence of self-compensation effects. In summary, we could demonstrate the necessity of Mg doping for achieving reasonable bio-functionalization of GaN surfaces.
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dc:title: Impact of Surface Chemistry and Doping Concentrations on Biofunctionalization of GaN/Ga-In-N Quantum Wells
modified: 2020-07-28T06:09:41Z
cp:subject: The development of sensitive biosensors, such as gallium nitride (GaN)-based quantum wells, transistors, etc., often makes it necessary to functionalize GaN surfaces with small molecules or eVen biomolecules, such as proteins. As a first step in surface functionalization, we have investigated silane adsorption, as well as the formation of very thin silane layers. In the next step, the immobilization of the tetrameric protein streptavidin (as well as the attachment of chemically modified iron transport protein ferritin (ferritin-biotin-rhodamine complex)) was realized on these films. The degree of functionalization of the GaN surfaces was determined by fluorescence measurements with fluorescent-labeled proteins; silane film thickness and surface roughness were estimated, and also other surface sensitive techniques were applied. The formation of a monolayer consisting of adsorbed organosilanes was accomplished on Mg-doped GaN surfaces, and also functionalization with proteins was achieved. We found that very high Mg doping reduced the amount of surface functionalized proteins. Most likely, this finding was a consequence of the lower concentration of ionizable Mg atoms in highly Mg-doped layers as a consequence of self-compensation effects. In summary, we could demonstrate the necessity of Mg doping for achieving reasonable bio-functionalization of GaN surfaces.
pdf:docinfo:subject: The development of sensitive biosensors, such as gallium nitride (GaN)-based quantum wells, transistors, etc., often makes it necessary to functionalize GaN surfaces with small molecules or eVen biomolecules, such as proteins. As a first step in surface functionalization, we have investigated silane adsorption, as well as the formation of very thin silane layers. In the next step, the immobilization of the tetrameric protein streptavidin (as well as the attachment of chemically modified iron transport protein ferritin (ferritin-biotin-rhodamine complex)) was realized on these films. The degree of functionalization of the GaN surfaces was determined by fluorescence measurements with fluorescent-labeled proteins; silane film thickness and surface roughness were estimated, and also other surface sensitive techniques were applied. The formation of a monolayer consisting of adsorbed organosilanes was accomplished on Mg-doped GaN surfaces, and also functionalization with proteins was achieved. We found that very high Mg doping reduced the amount of surface functionalized proteins. Most likely, this finding was a consequence of the lower concentration of ionizable Mg atoms in highly Mg-doped layers as a consequence of self-compensation effects. In summary, we could demonstrate the necessity of Mg doping for achieving reasonable bio-functionalization of GaN surfaces.
pdf:docinfo:creator: Nilanjon Naskar, Martin F. Schneidereit, Florian Huber, Sabyasachi Chakrabortty, Lothar Veith, Markus Mezger, Lutz Kirste, Theo Fuchs, Thomas Diemant, Tanja Weil, R. Jürgen Behm, Klaus Thonke and Ferdinand Scholz
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meta:author: Nilanjon Naskar, Martin F. Schneidereit, Florian Huber, Sabyasachi Chakrabortty, Lothar Veith, Markus Mezger, Lutz Kirste, Theo Fuchs, Thomas Diemant, Tanja Weil, R. Jürgen Behm, Klaus Thonke and Ferdinand Scholz
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Creation-Date: 2020-07-28T06:09:41Z
Author: Nilanjon Naskar, Martin F. Schneidereit, Florian Huber, Sabyasachi Chakrabortty, Lothar Veith, Markus Mezger, Lutz Kirste, Theo Fuchs, Thomas Diemant, Tanja Weil, R. Jürgen Behm, Klaus Thonke and Ferdinand Scholz
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Keywords: n-type GaN; p-type GaN; biosensor; chemical functionalization; protein adsorption; self-assembled monolayer
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dc:creator: Nilanjon Naskar, Martin F. Schneidereit, Florian Huber, Sabyasachi Chakrabortty, Lothar Veith, Markus Mezger, Lutz Kirste, Theo Fuchs, Thomas Diemant, Tanja Weil, R. Jürgen Behm, Klaus Thonke and Ferdinand Scholz
dcterms:created: 2020-07-28T06:09:41Z
Last-Modified: 2020-07-28T06:09:41Z
dcterms:modified: 2020-07-28T06:09:41Z
title: Impact of Surface Chemistry and Doping Concentrations on Biofunctionalization of GaN/Ga-In-N Quantum Wells
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pdf:docinfo:keywords: n-type GaN; p-type GaN; biosensor; chemical functionalization; protein adsorption; self-assembled monolayer
pdf:docinfo:modified: 2020-07-28T06:09:41Z
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creator: Nilanjon Naskar, Martin F. Schneidereit, Florian Huber, Sabyasachi Chakrabortty, Lothar Veith, Markus Mezger, Lutz Kirste, Theo Fuchs, Thomas Diemant, Tanja Weil, R. Jürgen Behm, Klaus Thonke and Ferdinand Scholz
dc:subject: n-type GaN; p-type GaN; biosensor; chemical functionalization; protein adsorption; self-assembled monolayer
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meta:keyword: n-type GaN; p-type GaN; biosensor; chemical functionalization; protein adsorption; self-assembled monolayer
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pdf:docinfo:created: 2020-07-28T06:09:41Z