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Poster

Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields

MPG-Autoren
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Pérez-Rodas,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Schulz,  H
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Heule,  R
Institutional Guests, Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen

https://www.ismrm.org/20/program_files/PP28.htm
(Zusammenfassung)

https://ww5.aievolution.com/ism2001/index.cfm?do=ev.viewEv&ev=3063
(Verlagsversion)

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Zitation

Pérez-Rodas, M., Schulz, H., Pohmann, R., Scheffler, K., & Heule, R. (2020). Towards intravascular BOLD signal characterization in balanced SSFP experiments of human blood at high to ultra-high fields. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Zitierlink: https://hdl.handle.net/21.11116/0000-0006-D873-5
Zusammenfassung
To fully understand the neurovascular fingerprint observed in BOLD experiments, extravascular and intravascular contributions have to be identified separately. Balanced steady-state free precession (bSSFP) imaging has demonstrated the ability for distortion-free fMRI with high microvascular sensitivity. However, the underlying intravascular contribution to BOLD bSSFP is not yet entirely known as literature R2 relaxation rates do not reflect the apparent diffusion-related R2 decrease in blood with shorter bSSFP refocusing intervals (TRs). This work thus focuses on characterizing the oxygen sensitivity of bSSFP in blood samples at high to ultra-high fields by means of passband signal differences and intrinsic R2 estimation.