English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  DetailsSummary

Released
Journal Article

Genetic diversity of HLA system in three populations from Sonora, Mexico: Ciudad Obregón, Hermosillo and rural Sonora

MPS-Authors
/persons/resource/persons214002

Barquera,  Rodrigo
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons202721

Clayton,  Stephen
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

External Resource
No external resources are shared
Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Uribe-Duarte, M. G., Aguilar-Campos, J. A., Barquera, R., Bravo-Acevedo, A., Clayton, S., Arrieta-Bolaños, E., et al. (2020). Genetic diversity of HLA system in three populations from Sonora, Mexico: Ciudad Obregón, Hermosillo and rural Sonora. Human Immunology, 81(9), 478-481. doi:10.1016/j.humimm.2019.05.013.


Cite as: https://hdl.handle.net/21.11116/0000-0007-301C-4
Abstract
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 439 Mexicans from the state of Sonora living in Ciudad Obregón (N = 143), Hermosillo (N = 99), and rural communities (N = 197) to obtain information regarding allelic and haplotypic frequencies. We find that the 13 most frequent haplotypes for the state of Sonora include nine Native American, three European and one Asian haplotypes. Admixture estimates revealed that the main genetic components in the state of Sonora are European (51.25 ± 2.90 by ML; 37.70 of European haplotypes) and Native American (43.35 ± 2.57 by ML; 39.64 of Native American haplotypes), while the African genetic component was less apparent (5.39 ± 2.54 by ML; 11.04 of African haplotypes).