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Deconvolution‐based distortion correction of EPI using analytic single‐voxel point‐spread functions

MPG-Autoren

Patzig,  Franz
Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Mildner,  Toralf
Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Schlumm,  Torsten
Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Müller,  Roland
Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Möller,  Harald E.
Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Zitation

Patzig, F., Mildner, T., Schlumm, T., Müller, R., & Möller, H. E. (2021). Deconvolution‐based distortion correction of EPI using analytic single‐voxel point‐spread functions. Magnetic Resonance in Medicine, 85(5), 2445-2461. doi:10.1002/mrm.28591.


Zitierlink: https://hdl.handle.net/21.11116/0000-0007-93CC-D
Zusammenfassung
Purpose

To develop a postprocessing algorithm that corrects geometric distortions due to spatial variations of the static magnetic field amplitude, B0, and effects from relaxation during signal acquisition in EPI.

Theory and Methods

An analytic, complex point‐spread function is deduced for k‐space trajectories of EPI variants and applied to corresponding acquisitions in a resolution phantom and in human volunteers at 3 T. With the analytic point‐spread function and experimental maps of B0 (and, optionally, the effective transverse relaxation time, urn:x-wiley:07403194:media:mrm28591:mrm28591-math-0004) as input, a point‐spread function matrix operator is devised for distortion correction by a Thikonov‐regularized deconvolution in image space. The point‐spread function operator provides additional information for an appropriate correction of the signal intensity distribution. A previous image combination algorithm for acquisitions with opposite phase blip polarities is adapted to the proposed method to recover destructively interfering signal contributions.

Results

Applications of the proposed deconvolution‐based distortion correction (“DecoDisCo”) algorithm demonstrate excellent distortion corrections and superior performance regarding the recovery of an undistorted intensity distribution in comparison to a multifrequency reconstruction. Examples include full and partial Fourier standard EPI scans as well as double‐shot center‐out trajectories. Compared with other distortion‐correction approaches, DecoDisCo permits additional deblurring to obtain sharper images in cases of significant urn:x-wiley:07403194:media:mrm28591:mrm28591-math-0005 effects.

Conclusion

Robust distortion corrections in EPI acquisitions are feasible with high quality by regularized deconvolution with an analytic point‐spread function. The general algorithm, which is publicly released on GitHub, can be straightforwardly adapted for specific EPI variants or other acquisition schemes.