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A genome sequence from a modern human skull over 45,000 years old from Zlatý kůň in Czechia

MPG-Autoren
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Prüfer,  Kay *       
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;
Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

/persons/resource/persons188736

Posth,  Cosimo *       
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;
Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

/persons/resource/persons247912

Yu,  He       
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons79177

Stoessel,  Alexander       
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;
Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

/persons/resource/persons189338

Spyrou,  Maria A.       
Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society;

/persons/resource/persons72801

Krause,  Johannes *       
Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

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Prüfer_Genome_NatEcoEvo_2021.pdf
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Zitation

Prüfer, K. *., Posth, C. *., Yu, H., Stoessel, A., Spyrou, M. A., Deviese, T., et al. (2021). A genome sequence from a modern human skull over 45,000 years old from Zlatý kůň in Czechia. Nature Ecology & Evolution, 5, 820-825. doi:10.1038/s41559-021-01443-x.


Zitierlink: https://hdl.handle.net/21.11116/0000-0008-468F-9
Zusammenfassung
Modern humans expanded into Eurasia more than 40,000 years ago following their dispersal out of Africa. These Eurasians carried ~2–3% Neanderthal ancestry in their genomes, originating from admixture with Neanderthals that took place sometime between 50,000 and 60,000 years ago, probably in the Middle East. In Europe, the modern human expansion preceded the disappearance of Neanderthals from the fossil record by 3,000–5,000 years. The genetic makeup of the first Europeans who colonized the continent more than 40,000 years ago remains poorly understood since few specimens have been studied. Here, we analyse a genome generated from the skull of a female individual from Zlatý kůň, Czechia. We found that she belonged to a population that appears to have contributed genetically neither to later Europeans nor to Asians. Her genome carries ~3% Neanderthal ancestry, similar to those of other Upper Palaeolithic hunter-gatherers. However, the lengths of the Neanderthal segments are longer than those observed in the currently oldest modern human genome of the ~45,000-year-old Ust’-Ishim individual from Siberia, suggesting that this individual from Zlatý kůň is one of the earliest Eurasian inhabitants following the expansion out of Africa.