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Poster

Deuterium Metabolic Imaging of the human brain at 9.4 T: Coil design and dynamic glucose uptake

MPG-Autoren
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Ruhm,  L
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Avdievich,  N       
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Ziegs,  T
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Henning,  A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;

Externe Ressourcen

https://www.ismrm.org/21/program-files/TeaserSlides/TeasersPresentations/1802-Teaser.html
(Zusammenfassung)

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Zitation

Ruhm, L., Avdievich, N., Ziegs, T., Nagel, A., De Feyter, H., de Graaf, R., et al. (2021). Deuterium Metabolic Imaging of the human brain at 9.4 T: Coil design and dynamic glucose uptake. Poster presented at 2021 ISMRM & SMRT Annual Meeting & Exhibition (ISMRM 2021).


Zitierlink: https://hdl.handle.net/21.11116/0000-0008-8640-8
Zusammenfassung
DMI (Deuterium Metabolic Imaging) is a technique that enables the investigation of metabolic turnover rates along predefined pathways non-invasively. In this work, we present first DMI data from the human brain at B0 = 9.4T and an investigation of the dynamic glucose uptake in different areas of the human head for healthy volunteers and after the oral administration of [6,6’-2H]-glucose. We present a dedicated phased array coil design and 2H MRSI data with high spatial resolution for water, glucose, Glx and lipid/lactate. Finally, we compare the uptake curves for different regions in the human head.