The colorectal cancer lipidome - identification of a robust tumor-specific 
lipid species signature.

Ecker, Josef; Benedetti, Elisa; Kindt, Alida S D; Höring, Marcus; Perl, Markus; Machmüller, Andrea Christel; Sichler, Anna; Plagge, Johannes; Wang, Yuting; Zeissig, Sebastian; Shevchenko, Andrej; Burkhardt, Ralph; Krumsiek, Jan; Liebisch, Gerhard; Janssen, Klaus-Peter

doi:10.1053/j.gastro.2021.05.009

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The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature.

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Wang, Yuting
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Shevchenko, Andrej
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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引用

Ecker, J., Benedetti, E., Kindt, A. S. D., Höring, M., Perl, M., Machmüller, A. C., Sichler, A., Plagge, J., Wang, Y., Zeissig, S., Shevchenko, A., Burkhardt, R., Krumsiek, J., Liebisch, G., & Janssen, K.-P. (2021). The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature. Gastroenterology,. doi:10.1053/j.gastro.2021.05.009.

引用: https://hdl.handle.net/21.11116/0000-0008-DB1B-4

要旨

Lipidomic changes were causally linked to metabolic diseases, but the scenario for colorectal cancer (CRC) is less clear. We investigated the CRC lipidome for putative tumour-specific alterations through analysis of three independent retrospective patient cohorts from two clinical centers, to derive a clinically useful signature.