Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells

Jentsch, S; Seufert, W; Sommer, T; Reins, H-A

doi:10.1016/0968-0004(90)90161-4

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Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells

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Jentsch, S
Jentsch Group, Friedrich Miescher Laboratory, Max Planck Society;

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Seufert, W
Jentsch Group, Friedrich Miescher Laboratory, Max Planck Society;

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Sommer, T
Jentsch Group, Friedrich Miescher Laboratory, Max Planck Society;

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Reins, H-A
Jentsch Group, Friedrich Miescher Laboratory, Max Planck Society;

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Citation

Jentsch, S., Seufert, W., Sommer, T., & Reins, H.-A. (1990). Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells. Trends in biochemical sciences, 15(5), 195-198. doi:10.1016/0968-0004(90)90161-4.

Cite as: https://hdl.handle.net/21.11116/0000-000A-DAE0-3

Abstract

Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress response.