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  Quantitative Metabolite Mapping of 12 Metabolites in the Human Brain

Wright, A., & Henning, A. (2022). Quantitative Metabolite Mapping of 12 Metabolites in the Human Brain. In Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022).

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 Creators:
Wright, AM1, Author                 
Henning, A2, Author                 
Affiliations:
1Institutional Guests, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_3505519              
2Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              

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 Abstract: Very short TR (TR < 300) MRSI is a popular method that enables fast acquisition of spectroscopic imaging data; however, raw metabolite signals following short TR acquisitions are influenced by strong T1-weighting. In order to gather more accurate images and to be able to relate MRSI results to SVS studies, it is valuable to correct for T1-weighting and to quantify MRSI images. This study presents results that utilize a voxel-specific, T1-correction method which is an advancement from more traditional methods that utilized average T1-corrections for metabolites. Fully sampled, single-slice 1H MRSI metabolite maps are presented for 12 metabolites.

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 Dates: 2022-05
 Publication Status: Published online
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Title: Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022)
Place of Event: London, UK
Start-/End Date: 2022-05-07 - 2022-05-12

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Title: Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting (ISMRM 2022)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3543 Start / End Page: - Identifier: -