og:image: https://cdn.ncbi.nlm.nih.gov/pubmed/persistent/pubmed-meta-image.png twitter:card: summary og:site_name: PubMed keywords: pmid:36669862, doi:10.1101/pdb.prot107750, Jens Seidel, William John Bradshaw, Dario Riccardo Valenzano, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE twitter:url: https://pubmed.ncbi.nlm.nih.gov/36669862/ citation_journal_title: Cold Spring Harbor protocols ncbi_pdid: abstract ncbi_phid: 19A900015D2E09B50000305C70A4C870.1.m_5 og:description: B cells undergo a process of somatic recombination leading to the synthesis of a staggering diversity of transmembrane and secreted antibodies. This process dates back to the evolution of jawed vertebrates and is pivotal to the origin of lymphocyte-based adaptive immune responses. Here, we optimized ? og:image:secure_url: https://cdn.ncbi.nlm.nih.gov/pubmed/persistent/pubmed-meta-image.png ncbi_db: pubmed citation_issn: 1559-6095 ncbi_pinger_stat_url: https://www.ncbi.nlm.nih.gov/stat dc:title: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri) - PubMed log_category: literature Content-Encoding: UTF-8 robots: index,nofollow,noarchive twitter:domain: pubmed.ncbi.nlm.nih.gov log_icons_present: true log_op: retrieve citation_abstract_html_url: https://pubmed.ncbi.nlm.nih.gov/36669862/ log_source_db: pubmed log_displayeduids: 36669862 ncbi_uid: 36669862 citation_doi: 10.1101/pdb.prot107750 Content-Language: en theme-color: #20558a citation_title: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri) ncbi_sg_optimize_id: citation_publisher: Cold Spring Harb Protoc HandheldFriendly: True description: B cells undergo a process of somatic recombination leading to the synthesis of a staggering diversity of transmembrane and secreted antibodies. This process dates back to the evolution of jawed vertebrates and is pivotal to the origin of lymphocyte-based adaptive immune responses. Here, we optimized ? citation_date: 01/20/2023 title: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri) - PubMed ncbi_cost_center: pubmed twitter:image: https://cdn.ncbi.nlm.nih.gov/pubmed/persistent/pubmed-meta-image.png uid: 36669862 ncbi_pinger_gtm_track: true Content-Type: text/html; charset=UTF-8 X-Parsed-By: org.apache.tika.parser.DefaultParser og:type: website twitter:title: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri) - PubMed citation_pmid: 36669862 ncbi_app: pubmed og:title: Sequencing the Immunoglobulin Heavy-Chain Locus (IgH) in Turquoise Killifish ( Nothobranchius furzeri) - PubMed citation_authors: Seidel J;Bradshaw WJ;Valenzano DR; X-UA-Compatible: IE=edge referrer: origin-when-cross-origin MobileOptimized: 320 viewport: width=device-width, initial-scale=1.0 twitter:description: B cells undergo a process of somatic recombination leading to the synthesis of a staggering diversity of transmembrane and secreted antibodies. This process dates back to the evolution of jawed vertebrates and is pivotal to the origin of lymphocyte-based adaptive immune responses. Here, we optimized ? og:url: https://pubmed.ncbi.nlm.nih.gov/36669862/