English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Poster

Understanding signal specificity in fMRI: bSSFP vs. GRE-EPI signal dependence on cortical orientation to B0 at 9.4 Tesla

MPS-Authors
/persons/resource/persons272752

Ramadan,  D
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons192600

Bause,  J       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons238878

Mueller,  S       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons215985

Bosch,  D       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler,  K       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Resource

https://www.ismrm.org/24/docs/24ToC.pdf
(Abstract)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Ramadan, D., Bause, J., Mueller, S., Bosch, D., Stirnberg, R., Ehses, P., et al. (2024). Understanding signal specificity in fMRI: bSSFP vs. GRE-EPI signal dependence on cortical orientation to B0 at 9.4 Tesla. Poster presented at ISMRM & ISMRT Annual Meeting & Exhibition 2024, Singapore.


Cite as: https://hdl.handle.net/21.11116/0000-000F-396F-6
Abstract
Motivation: GRE-EPI, the most widely used sequence for BOLD fMRI, is highly biased towards large draining veins that follow the cortical curvature and influence the surrounding magnetic field in an orientation-dependent manner increasing with field strength. Goal(s): This work aims to investigate large vein biases resulting in cortical orientation-dependent signal variations in GRE-EPI and bSSFP resting-state fMRI signals. Approach: We compared 2D and 3D GRE-EPI with 3D bSSFP rs-fMRI signal fluctuations in their dependence on the cortical orientation to B in five subjects at 9.4 Tesla. Results: Unlike GRE-EPI, intra- and inter-subject comparisons revealed no dependence of bSSFP on the cortical orientation to B . Impact: Fluctuations in the GRE-EPI signal are highly dependent on the cortical orientation and depth. This was not observed with bSSFP, demonstrating the potentially higher specificity of bSSFP for smaller veins, closer to brain activation at field strengths ≥ 7 Tesla.