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Meeting Abstract

13C imaging of pyruvate with SABRE at Ultra-Low field

MPS-Authors
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Kempf,  N       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Engelmann,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Boldt,  J
Fine Mechanical Workshop, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler,  K       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Buckenmaier,  K       
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Kempf, N., Körber, R., Plaumann, M., Pravdivtsev, A., Engelmann, J., Boldt, J., et al. (2024). 13C imaging of pyruvate with SABRE at Ultra-Low field. In DACH-ISMRM Annual Meeting 2024 (pp. 42-43).


Cite as: https://hdl.handle.net/21.11116/0000-000F-C024-F
Abstract
The ultra-low magnetic field regime
opens up new opportunities for magnetic
resonance through parahydrogen-based
hyperpolarization. Our in situ combination of
Signal Amplification by Reversible Exchange
(SABRE) with a Superconducting Quantum
Interference Device (SQUID) embodies a
highly versatile MRI system. Recent results
demonstrate 3-dimensional 13C imaging of [1-
13C] pyruvate in a phantom at twice the Earth’s
magnetic field with sub-millimeter resolution.
The results pave the way for in vivo ULF
imaging with SABRE.