Supplementary Materials
Molecular architecture of the human U4/U6.U5 tri-snRNP
Dmitry E. Agafonov, Berthold Kastner, Olexandr Dybkov, Romina V. Hofele, Wen-Ti Liu, Henning Urlaub, Reinhard Lührmann, Holger Stark
Materials/Methods, Supplementary Text, Tables, Figures, and/or References
- Materials and Methods
- Figs. S1 to S16
- Table S1
- Captions for table S2 and movie S1
- References
- BS3-crosslinks between and within known structured regions of human
tri-snRNP proteins
Statistics (Spectral Counts and Scoremax) of the CX-MS data for the proteins of the purified human tri-snRNP. “Inter" and “Intra” indicate inter-protein and intra-protein crosslinks, respectively. Numbers in the Residue 1 and 2 columns indicate the position of the crosslinked lysine or N-terminal methionine residue.
Images, Video, and Other Other Media
- The movie shows the tri-snRNP 3D structure rotating along its long axis. The fitted proteins and RNA parts of the tri-snRNP are shown in the semi-transparent envelope of the EM density.
