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Physics > Biological Physics

Title:Skewness and Kurtosis in Statistical Kinetics

Abstract: We obtain lower and upper bounds on the skewness and kurtosis associated with the cycle completion time of unicyclic enzymatic reaction schemes. Analogous to a well known lower bound on the randomness parameter, the lower bounds on skewness and kurtosis are related to the number of intermediate states in the underlying chemical reaction network. Our results demonstrate that evaluating these higher order moments with single molecule data can lead to information about the enzymatic scheme that is not contained in the randomness parameter.
Comments: 5+3 pages, 4 figures
Subjects: Biological Physics (physics.bio-ph); Statistical Mechanics (cond-mat.stat-mech); Chemical Physics (physics.chem-ph)
Journal reference: Phys. Rev. Lett. 115, 188103 (2015)
DOI: 10.1103/PhysRevLett.115.188103
Cite as: arXiv:1510.03279 [physics.bio-ph]
  (or arXiv:1510.03279v1 [physics.bio-ph] for this version)

Submission history

From: Andre Cardoso Barato [view email]
[v1] Mon, 12 Oct 2015 13:49:10 UTC (302 KB)