Video 4: Supplementary Video 4

FromEngineered non-Mendelian inheritance of entire parental genomes in C. elegans

Journal name:
Nature Biotechnology
Year published:
Published online
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An example of segregation of the paternal chromosomes to the P lineage. Anterior is to the left. The paternal pronucleus can be formally identified because it is located further to the posterior and has the two centrosomes attached. The maternal pronucleus is located initially in the anterior, has no centrosomes attached and is more mobile. Thus, the two pronuclei meet in the posterior to form the PCC. The PCC is then pulled apart so that the maternal pronucleus forms a monopolar spindle in the anterior, and the paternal pronucleus forms a monopolar spindle in the posterior. Frames were taken every 20 seconds and the display rate is 3 frames per second.

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