date: 2021-10-14T07:53:08Z
pdf:unmappedUnicodeCharsPerPage: 17
pdf:PDFVersion: 1.7
pdf:docinfo:title: Mesoporous One-Component Gold Microshells as 3D SERS Substrates
xmp:CreatorTool: LaTeX with hyperref
Keywords: calcium carbonate; vaterite; hard templating; Raman spectroscopy; microparticles
access_permission:modify_annotations: true
access_permission:can_print_degraded: true
subject: Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for label-free analysis that has found a broad spectrum of applications in material, chemical, and biomedical sciences. In recent years, a great interest has been witnessed in the rational design of SERS substrates to amplify Raman signals and optionally allow for the selective detection of analytes, which is especially essential and challenging for biomedical applications. In this study, hard templating of noble metals is proposed as a novel approach for the design of one-component tailor-made SERS platforms. Porous Au microparticles were fabricated via dual ex situ adsorption of Au nanoparticles and in situ reduction of HAuCl4 on mesoporous sacrificial microcrystals of vaterite CaCO3. Elimination of the microcrystals at mild conditions resulted in the formation of stable mesoporous one-component Au microshells. SERS performance of the microshells at very low 0.4 W laser power was probed using rhodamine B and bovine serum albumin showing enhancement factors of 2  108 and 8  108, respectively. The proposed strategy opens broad avenues for the design and scalable fabrication of one-component porous metal particles that can serve as superior SERS platforms possessing both excellent plasmonic properties and the possibility of selective inclusion of analyte molecules and/or SERS nanotags for highly specific SERS analysis.
dc:creator: Anna S. Vikulina, Inna Y. Stetsyura, M. Serdar Onses, Erkan Yilmaz, Andre G. Skirtach and Dmitry Volodkin
dcterms:created: 2021-10-14T07:14:23Z
Last-Modified: 2021-10-14T07:53:08Z
dcterms:modified: 2021-10-14T07:53:08Z
dc:format: application/pdf; version=1.7
title: Mesoporous One-Component Gold Microshells as 3D SERS Substrates
Last-Save-Date: 2021-10-14T07:53:08Z
pdf:docinfo:creator_tool: LaTeX with hyperref
access_permission:fill_in_form: true
pdf:docinfo:keywords: calcium carbonate; vaterite; hard templating; Raman spectroscopy; microparticles
pdf:docinfo:modified: 2021-10-14T07:53:08Z
meta:save-date: 2021-10-14T07:53:08Z
pdf:encrypted: false
dc:title: Mesoporous One-Component Gold Microshells as 3D SERS Substrates
modified: 2021-10-14T07:53:08Z
cp:subject: Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for label-free analysis that has found a broad spectrum of applications in material, chemical, and biomedical sciences. In recent years, a great interest has been witnessed in the rational design of SERS substrates to amplify Raman signals and optionally allow for the selective detection of analytes, which is especially essential and challenging for biomedical applications. In this study, hard templating of noble metals is proposed as a novel approach for the design of one-component tailor-made SERS platforms. Porous Au microparticles were fabricated via dual ex situ adsorption of Au nanoparticles and in situ reduction of HAuCl4 on mesoporous sacrificial microcrystals of vaterite CaCO3. Elimination of the microcrystals at mild conditions resulted in the formation of stable mesoporous one-component Au microshells. SERS performance of the microshells at very low 0.4 W laser power was probed using rhodamine B and bovine serum albumin showing enhancement factors of 2  108 and 8  108, respectively. The proposed strategy opens broad avenues for the design and scalable fabrication of one-component porous metal particles that can serve as superior SERS platforms possessing both excellent plasmonic properties and the possibility of selective inclusion of analyte molecules and/or SERS nanotags for highly specific SERS analysis.
pdf:docinfo:subject: Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for label-free analysis that has found a broad spectrum of applications in material, chemical, and biomedical sciences. In recent years, a great interest has been witnessed in the rational design of SERS substrates to amplify Raman signals and optionally allow for the selective detection of analytes, which is especially essential and challenging for biomedical applications. In this study, hard templating of noble metals is proposed as a novel approach for the design of one-component tailor-made SERS platforms. Porous Au microparticles were fabricated via dual ex situ adsorption of Au nanoparticles and in situ reduction of HAuCl4 on mesoporous sacrificial microcrystals of vaterite CaCO3. Elimination of the microcrystals at mild conditions resulted in the formation of stable mesoporous one-component Au microshells. SERS performance of the microshells at very low 0.4 W laser power was probed using rhodamine B and bovine serum albumin showing enhancement factors of 2  108 and 8  108, respectively. The proposed strategy opens broad avenues for the design and scalable fabrication of one-component porous metal particles that can serve as superior SERS platforms possessing both excellent plasmonic properties and the possibility of selective inclusion of analyte molecules and/or SERS nanotags for highly specific SERS analysis.
Content-Type: application/pdf
pdf:docinfo:creator: Anna S. Vikulina, Inna Y. Stetsyura, M. Serdar Onses, Erkan Yilmaz, Andre G. Skirtach and Dmitry Volodkin
X-Parsed-By: org.apache.tika.parser.DefaultParser
creator: Anna S. Vikulina, Inna Y. Stetsyura, M. Serdar Onses, Erkan Yilmaz, Andre G. Skirtach and Dmitry Volodkin
meta:author: Anna S. Vikulina, Inna Y. Stetsyura, M. Serdar Onses, Erkan Yilmaz, Andre G. Skirtach and Dmitry Volodkin
dc:subject: calcium carbonate; vaterite; hard templating; Raman spectroscopy; microparticles
meta:creation-date: 2021-10-14T07:14:23Z
created: 2021-10-14T07:14:23Z
access_permission:extract_for_accessibility: true
access_permission:assemble_document: true
xmpTPg:NPages: 10
Creation-Date: 2021-10-14T07:14:23Z
pdf:charsPerPage: 3852
access_permission:extract_content: true
access_permission:can_print: true
meta:keyword: calcium carbonate; vaterite; hard templating; Raman spectroscopy; microparticles
Author: Anna S. Vikulina, Inna Y. Stetsyura, M. Serdar Onses, Erkan Yilmaz, Andre G. Skirtach and Dmitry Volodkin
producer: pdfTeX-1.40.21
access_permission:can_modify: true
pdf:docinfo:producer: pdfTeX-1.40.21
pdf:docinfo:created: 2021-10-14T07:14:23Z