Researcher Portfolio
Haefele, M.
High Performance Computer for Fusion Applications - High Level Support Core Team, Max Planck Institute for Plasma Physics, Max Planck Society, Numerical Methods in Plasma Physics (NMPP), Max Planck Institute for Plasma Physics, Max Planck Society, Tokamak Theory (TOK), Max Planck Institute for Plasma Physics, Max Planck Society
Researcher Profile
Position: Tokamak Theory (TOK), Max Planck Institute for Plasma Physics, Max Planck Society
Position: High Performance Computer for Fusion Applications - High Level Support Core Team, Max Planck Institute for Plasma Physics, Max Planck Society
Position: Numerical Methods in Plasma Physics (NMPP), Max Planck Institute for Plasma Physics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons109269
Publications
(1 - 25 of 81)
: Schmitt, L. T., Paszkowski-Rogacz, M., Jug, F., & Buchholz, F. (2022). Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications, 13(1): 7966. doi:10.1038/s41467-022-35614-6. [PubMan] : Graindorge, A., Pinheiro, I., Nawrocka, A., Mallory, A. C., Tsvetkov, P., Gil, N., Carolis, C., Buchholz, F., Ulitsky, I., Heard, E., Taipale, M., & Shkumatava, A. (2019). In-cell identification and measurement of RNA-protein interactions. Nature communications, 10(1): 5317. doi:10.1038/s41467-019-13235-w. [PubMan] : Sayed, S., Paszkowski-Rogacz, M., Schmitt, L. T., & Buchholz, F. (2019). CRISPR/Cas9 as a tool to dissect cancer mutations. Methods (San Diego, Calif.), 164/165, 36-48. doi:10.1016/j.ymeth.2019.05.007. [PubMan] : Güneş, C., Paszkowski-Rogacz, M., Rahmig, S., Khattak, S., Camgöz, A., Wermke, M., Dahl, A., Bornhäuser, M., Waskow, C., & Buchholz, F. (2019). Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator. Stem cell reports, 12(5), 1084-1098. doi:10.1016/j.stemcr.2019.03.012. [PubMan] : Noack, F., Pataskar, A., Schneider, M., Buchholz, F., Tiwari, V. K., & Calegari, F. (2019). Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis. Life science alliance, 2(2): e201900331, pp. 1-1. doi:10.26508/lsa.201900331. [PubMan] : Karimova, M., Baker, O., Camgoz, A., Naumann, R., Buchholz, F., & Anastassiadis, K. (2018). A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination. Scientific reports, 8(1): 14453. doi:10.1038/s41598-018-32802-7. [PubMan] : Senserrich, J., Batsivari, A., Rybtsov, S., Gordon-Keylock, S., Souilhol, C., Buchholz, F., Hills, D., Zhao, S., & Medvinsky, A. (2018). Analysis of Runx1 Using Induced Gene Ablation Reveals Its Essential Role in Pre-liver HSC Development and Limitations of an In Vivo Approach. Stem cell reports, 11(3), 784-794. doi:10.1016/j.stemcr.2018.08.004. [PubMan] : Aleksandrov, R., Dotchev, A., Poser, I., Krastev, D., Georgiev, G., Panova, G. C., Babukov, Y., Danovski, G., Dyankova, T., Hubatsch, L., Ivanova, A., Atemin, A., Nedelcheva-Veleva, M. N., Hasse, S., Sarov, M., Buchholz, F., Hyman, A., Grill, S. W., & Stoynov, S. (2018). Protein Dynamics in Complex DNA Lesions. Molecular cell, 69(6), 1046-1061. doi:10.1016/j.molcel.2018.02.016. [PubMan] : Kumar, M., Joseph, S., Augsburg, M., Bogdanova, A., Drechsel, D. N., Vastenhouw, N., Buchholz, F., Gentzel, M., & Shevchenko, A. (2018). MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting. Molecular & cellular proteomics: MCP, 17(2), 384-396. doi:10.1074/mcp.O117.067082. [PubMan] : Winzi, M., Vila, N. C., Paszkowski-Rogacz, M., Ding, L., Noack, S., Theis, M., Butter, F., & Buchholz, F. (2018). The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells. PloS one, 13(1): e191682. doi:10.1371/journal.pone.0191682. [PubMan] : Bäumer, N., Rehkämper, J., Appel, N., Terheyden, L., Hartmann, W., Wardelmann, E., Buchholz, F., Müller-Tidow, C., Berdel, W. E., & Bäumer, S. (2018). Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth. PloS one, 13(7): 200163. doi:10.1371/journal.pone.0200163. [PubMan] : Chakraborty, D., Paszkowski-Rogacz, M., Berger, N., Ding, L., Mircetic, J., Fu, J., Iesmantavicius, V., Choudhary, C., Anastassiadis, K., Stewart, A. F., & Buchholz, F. (2017). lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1. Cell reports, 21(11), 3012-3021. doi:10.1016/j.celrep.2017.11.045. [PubMan] : Mircetic, J., Dietrich, A., Paszkowski-Rogacz, M., Krause, M., & Buchholz, F. (2017). Development of a genetic sensor that eliminates p53 deficient cells. Nature communications, 8(1): 1463. doi:10.1038/s41467-017-01688-w. [PubMan] : Toyoda, Y., Cattin, C. J., Stewart, M. P., Poser, I., Theis, M., Kurzchalia, T. V., Buchholz, F., Hyman, A., & Müller, D. J. (2017). Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding. Nature communications, 8(1): 1266. doi:10.1038/s41467-017-01147-6. [PubMan] : Meinke, G., Karpinski, J., Buchholz, F., & Bohm, A. (2017). Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA. Nucleic acids research, 45(16), 9726-9740. doi:10.1093/nar/gkx603. [PubMan] : Jahn, A., Rane, G., Paszkowski-Rogacz, M., Sayols, S., Bluhm, A., Han, C.-T., Draškovič, I., Londoño-Vallejo, J. A., Kumar, A. P., Buchholz, F., Butter, F., & Kappei, D. (2017). ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO reports, 18(6), 929-946. doi:10.15252/embr.201744095. [PubMan] : Mircetic, J., Steinebrunner, I., Ding, L., Fei, J., Bogdanova, A., Drechsel, D. N., & Buchholz, F. (2017). Purified Cas9 Fusion Proteins for Advanced Genome Manipulation. Small Methods, 1(4): 1600052. doi:10.1002/smtd.201600052. [PubMan] : Karpinski, J., Schneider, M., Lansing, F., Hauber, J., & Buchholz, F. (2017). Designer-Rekombinasen für präzises Genome Editing. BIOspektrum, 23(2), 151-154. doi:10.1007/s12268-017-0780-x. [PubMan] : Kappei, D., Scheibe, M., Paszkowski-Rogacz, M., Bluhm, A., Gossmann, T. I., Dietz, S., Dejung, M., Herlyn, H., Buchholz, F., Mann, M., & Butter, F. (2017). Phylointeractomics reconstructs functional evolution of protein binding. Nature communications, 8: 14334. doi:10.1038/ncomms14334. [PubMan] : Korotkevich, E., Niwayama, R., Courtois, A., Friese, S., Berger, N., Buchholz, F., & Hiiragi, T. (2017). The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Developmental cell, 40(3), 235-247. doi:10.1016/j.devcel.2017.01.006. [PubMan] : Gebler, C., Lohoff, T., Paszkowski-Rogacz, M., Mircetic, J., Chakraborty, D., Camgoz, A., Hamann, M. V., Theis, M., Thiede, C., & Buchholz, F. (2017). Inactivation of Cancer Mutations Utilizing CRISPR/Cas9. Journal of the National Cancer Institute, 109(1): djw183. doi:10.1093/jnci/djw183. [PubMan] : Karimova, M., Splith, V., Karpinski, J., Pisabarro, M. T., & Buchholz, F. (2016). Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering. Scientific Reports, 6: 30130. [PubMan] : Karpinski, J., Hauber, I., Chemnitz, J., Schäfer, C., Paszkowski-Rogacz, M., Chakraborty, D., Beschorner, N., Hofmann-Sieber, H., Lange, U. C., Grundhoff, A., Hackmann, K., Schrock, E., Abi-Ghanem, J., Pisabarro, M. T., Surendranath, V., Schambach, A., Lindner, C., Lunzen, J. v., Hauber, J., & Buchholz, F. (2016). Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nature biotechnology, 34(4), 401-409. [PubMan] : Theis, M., Paszkowski-Rogacz, M., Weisswange, I., Chakraborty, D., & Buchholz, F. (2015). Targeting Human Long Noncoding Transcripts by Endoribonuclease-Prepared siRNAs. Journal of Biomolecular Screening, 20(8), 1018-1026. [PubMan] : Hein, M. Y., Hubner, N. C., Poser, I., Cox, J., Nagaraj, N., Toyoda, Y., Gak, I. A., Weisswange, I., Mansfeld, J., Buchholz, F., Hyman, A., & Mann, M. (2015). A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. Cell, 163(3), 712-723. [PubMan]