Researcher Portfolio
Buchholz, Frank
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society
Researcher Profile
Position: Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons219042
Publications
(1 - 25 of 81)
: Schmitt, L. T., Paszkowski-Rogacz, M., Jug, F., & Buchholz, F. (2022). Prediction of designer-recombinases for DNA editing with generative deep learning. Nature communications, 13(1): 7966. doi:10.1038/s41467-022-35614-6. [PubMan] : Graindorge, A., Pinheiro, I., Nawrocka, A., Mallory, A. C., Tsvetkov, P., Gil, N., Carolis, C., Buchholz, F., Ulitsky, I., Heard, E., Taipale, M., & Shkumatava, A. (2019). In-cell identification and measurement of RNA-protein interactions. Nature communications, 10(1): 5317. doi:10.1038/s41467-019-13235-w. [PubMan] : Sayed, S., Paszkowski-Rogacz, M., Schmitt, L. T., & Buchholz, F. (2019). CRISPR/Cas9 as a tool to dissect cancer mutations. Methods (San Diego, Calif.), 164/165, 36-48. doi:10.1016/j.ymeth.2019.05.007. [PubMan] : Güneş, C., Paszkowski-Rogacz, M., Rahmig, S., Khattak, S., Camgöz, A., Wermke, M., Dahl, A., Bornhäuser, M., Waskow, C., & Buchholz, F. (2019). Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator. Stem cell reports, 12(5), 1084-1098. doi:10.1016/j.stemcr.2019.03.012. [PubMan] : Noack, F., Pataskar, A., Schneider, M., Buchholz, F., Tiwari, V. K., & Calegari, F. (2019). Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis. Life science alliance, 2(2): e201900331, pp. 1-1. doi:10.26508/lsa.201900331. [PubMan] : Karimova, M., Baker, O., Camgoz, A., Naumann, R., Buchholz, F., & Anastassiadis, K. (2018). A single reporter mouse line for Vika, Flp, Dre, and Cre-recombination. Scientific reports, 8(1): 14453. doi:10.1038/s41598-018-32802-7. [PubMan] : Senserrich, J., Batsivari, A., Rybtsov, S., Gordon-Keylock, S., Souilhol, C., Buchholz, F., Hills, D., Zhao, S., & Medvinsky, A. (2018). Analysis of Runx1 Using Induced Gene Ablation Reveals Its Essential Role in Pre-liver HSC Development and Limitations of an In Vivo Approach. Stem cell reports, 11(3), 784-794. doi:10.1016/j.stemcr.2018.08.004. [PubMan] : Aleksandrov, R., Dotchev, A., Poser, I., Krastev, D., Georgiev, G., Panova, G. C., Babukov, Y., Danovski, G., Dyankova, T., Hubatsch, L., Ivanova, A., Atemin, A., Nedelcheva-Veleva, M. N., Hasse, S., Sarov, M., Buchholz, F., Hyman, A., Grill, S. W., & Stoynov, S. (2018). Protein Dynamics in Complex DNA Lesions. Molecular cell, 69(6), 1046-1061. doi:10.1016/j.molcel.2018.02.016. [PubMan] : Kumar, M., Joseph, S., Augsburg, M., Bogdanova, A., Drechsel, D. N., Vastenhouw, N., Buchholz, F., Gentzel, M., & Shevchenko, A. (2018). MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting. Molecular & cellular proteomics: MCP, 17(2), 384-396. doi:10.1074/mcp.O117.067082. [PubMan] : Winzi, M., Vila, N. C., Paszkowski-Rogacz, M., Ding, L., Noack, S., Theis, M., Butter, F., & Buchholz, F. (2018). The long noncoding RNA lncR492 inhibits neural differentiation of murine embryonic stem cells. PloS one, 13(1): e191682. doi:10.1371/journal.pone.0191682. [PubMan] : Bäumer, N., Rehkämper, J., Appel, N., Terheyden, L., Hartmann, W., Wardelmann, E., Buchholz, F., Müller-Tidow, C., Berdel, W. E., & Bäumer, S. (2018). Downregulation of PIK3CA via antibody-esiRNA-complexes suppresses human xenograft tumor growth. PloS one, 13(7): 200163. doi:10.1371/journal.pone.0200163. [PubMan] : Chakraborty, D., Paszkowski-Rogacz, M., Berger, N., Ding, L., Mircetic, J., Fu, J., Iesmantavicius, V., Choudhary, C., Anastassiadis, K., Stewart, A. F., & Buchholz, F. (2017). lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1. Cell reports, 21(11), 3012-3021. doi:10.1016/j.celrep.2017.11.045. [PubMan] : Mircetic, J., Dietrich, A., Paszkowski-Rogacz, M., Krause, M., & Buchholz, F. (2017). Development of a genetic sensor that eliminates p53 deficient cells. Nature communications, 8(1): 1463. doi:10.1038/s41467-017-01688-w. [PubMan] : Toyoda, Y., Cattin, C. J., Stewart, M. P., Poser, I., Theis, M., Kurzchalia, T. V., Buchholz, F., Hyman, A., & Müller, D. J. (2017). Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding. Nature communications, 8(1): 1266. doi:10.1038/s41467-017-01147-6. [PubMan] : Meinke, G., Karpinski, J., Buchholz, F., & Bohm, A. (2017). Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA. Nucleic acids research, 45(16), 9726-9740. doi:10.1093/nar/gkx603. [PubMan] : Jahn, A., Rane, G., Paszkowski-Rogacz, M., Sayols, S., Bluhm, A., Han, C.-T., Draškovič, I., Londoño-Vallejo, J. A., Kumar, A. P., Buchholz, F., Butter, F., & Kappei, D. (2017). ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator. EMBO reports, 18(6), 929-946. doi:10.15252/embr.201744095. [PubMan] : Mircetic, J., Steinebrunner, I., Ding, L., Fei, J., Bogdanova, A., Drechsel, D. N., & Buchholz, F. (2017). Purified Cas9 Fusion Proteins for Advanced Genome Manipulation. Small Methods, 1(4): 1600052. doi:10.1002/smtd.201600052. [PubMan] : Karpinski, J., Schneider, M., Lansing, F., Hauber, J., & Buchholz, F. (2017). Designer-Rekombinasen für präzises Genome Editing. BIOspektrum, 23(2), 151-154. doi:10.1007/s12268-017-0780-x. [PubMan] : Kappei, D., Scheibe, M., Paszkowski-Rogacz, M., Bluhm, A., Gossmann, T. I., Dietz, S., Dejung, M., Herlyn, H., Buchholz, F., Mann, M., & Butter, F. (2017). Phylointeractomics reconstructs functional evolution of protein binding. Nature communications, 8: 14334. doi:10.1038/ncomms14334. [PubMan] : Korotkevich, E., Niwayama, R., Courtois, A., Friese, S., Berger, N., Buchholz, F., & Hiiragi, T. (2017). The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Developmental cell, 40(3), 235-247. doi:10.1016/j.devcel.2017.01.006. [PubMan] : Gebler, C., Lohoff, T., Paszkowski-Rogacz, M., Mircetic, J., Chakraborty, D., Camgoz, A., Hamann, M. V., Theis, M., Thiede, C., & Buchholz, F. (2017). Inactivation of Cancer Mutations Utilizing CRISPR/Cas9. Journal of the National Cancer Institute, 109(1): djw183. doi:10.1093/jnci/djw183. [PubMan] : Karimova, M., Splith, V., Karpinski, J., Pisabarro, M. T., & Buchholz, F. (2016). Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering. Scientific Reports, 6: 30130. [PubMan] : Karpinski, J., Hauber, I., Chemnitz, J., Schäfer, C., Paszkowski-Rogacz, M., Chakraborty, D., Beschorner, N., Hofmann-Sieber, H., Lange, U. C., Grundhoff, A., Hackmann, K., Schrock, E., Abi-Ghanem, J., Pisabarro, M. T., Surendranath, V., Schambach, A., Lindner, C., Lunzen, J. v., Hauber, J., & Buchholz, F. (2016). Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nature biotechnology, 34(4), 401-409. [PubMan] : Theis, M., Paszkowski-Rogacz, M., Weisswange, I., Chakraborty, D., & Buchholz, F. (2015). Targeting Human Long Noncoding Transcripts by Endoribonuclease-Prepared siRNAs. Journal of Biomolecular Screening, 20(8), 1018-1026. [PubMan] : Hein, M. Y., Hubner, N. C., Poser, I., Cox, J., Nagaraj, N., Toyoda, Y., Gak, I. A., Weisswange, I., Mansfeld, J., Buchholz, F., Hyman, A., & Mann, M. (2015). A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances. Cell, 163(3), 712-723. [PubMan]