Researcher Portfolio
Franzmann, Titus
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society
Researcher Profile
Position: Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons219166
Publications
(1 - 25 of 28)
: Verde, E. M., Antoniani, F., Mediani, L., Secco, V., Crotti, S., Ferrara, M. C., Vinet, J., Sergeeva, A., Yan, X., Hoege, C., Stuani, C., Paron, F., Kao, T.-T., Shrivastava, R., Polanowska, J., Bailly, A., Rosa, A., Aronica, E., Goswami, A., Shneider, N., Hyman, A., Buratti, E., Xirodimas, D., Franzmann, T., Alberti, S., & Carra, S. (2025). SUMO2/3 conjugation of TDP-43 protects against aggregation. Science advances, 11(8): 2475. doi:10.1126/sciadv.adq2475. [PubMan] : Beck, T., Linden, L.-M.-v.-d., Borcherds, W. M., Kim, K., Schlüßler, R., Müller, P., Franzmann, T., Möckel, C., Goswami, R., Leaver, M., Mittag, T., Alberti, S., & Guck, J. (2024). Optical characterization of molecular interaction strength in protein condensates. Molecular biology of the cell, 35(12): ar154. doi:10.1091/mbc.E24-03-0128. [PubMan] : Altamirano, C. D., Kang, M.-K., Jordan, M. A., Borianne, T., Dilmen, I., Gnädig, M., Appen, A. v., Honigmann, A., Franzmann, T., & Alberti, S. (2024). eIF4F is a thermo-sensing regulatory node in the translational heat shock response. Molecular cell, 84(9), 1727-1741. doi:10.1016/j.molcel.2024.02.038. [PubMan] : Chappidi, N., Quail, T., Doll, S., Vogel, L. T., Aleksandrov, R., Felekyan, S., Kühnemuth, R., Stoynov, S., Seidel, C. A. M., Brugués, J., Jahnel, M., Franzmann, T., & Alberti, S. (2024). PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends. Cell, 187(4), 945-961. doi:10.1016/j.cell.2024.01.015. [PubMan] : Arter, W. E., Qi, R., Erkamp, N. A., Krainer, G., Didi, K., Welsh, T. J., Acker, J., Nixon-Abell, J., Qamar, S., Guillén-Boixet, J., Franzmann, T., Kuster, D., Hyman, A., Borodavka, A., George-Hyslop, P. S., Alberti, S., & Knowles, T. P. J. (2022). Biomolecular condensate phase diagrams with a combinatorial microdroplet platform. Nature communications, 13(1): 7845. doi:10.1038/s41467-022-35265-7. [PubMan] : Kar, M., Dar, F., Welsh, T. J., Vogel, L. T., Kühnemuth, R., Majumdar, A., Krainer, G., Franzmann, T., Alberti, S., Seidel, C. A. M., Knowles, T. P. J., Hyman, A., & Pappu, R. V. (2022). Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions. Proceedings of the National Academy of Sciences of the United States of America, 119(28): e2202222119. doi:10.1073/pnas.2202222119. [PubMan] : Krainer, G., Welsh, T. J., Joseph, J. A., Espinosa, J. R., Wittmann, S., Csilléry, E. d., Sridhar, A., Toprakcioglu, Z., Gudiškytė, G., Czekalska, M. A., Arter, W. E., Guillén-Boixet, J., Franzmann, T., Qamar, S., George-Hyslop, P. S., Hyman, A., Collepardo-Guevara, R., Alberti, S., & Knowles, T. P. J. (2021). Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions. Nature communications, 12(1): 1085. doi:10.1038/s41467-021-21181-9. [PubMan] : Jawerth, L., Fischer-Friedrich, E., Saha, S., Wang, J., Franzmann, T., Zhang, X., Sachweh, J., Ruer, M., Ijavi, M., Saha, S., Mahamid, J., Hyman, A., & Jülicher, F. (2020). Protein condensates as aging Maxwell fluids. Science (New York, N.Y.), 370(6522), 1317-1323. doi:10.1126/science.aaw4951. [PubMan] : Jawerth, L., Fischer-Friedrich, E., Saha, S., Wang, J., Franzmann, T., Zhang, X., Sachweh, J., Ruer, M., Ijavi, M., Saha, S., Mahamid, J., Hyman, A., & Jülicher, F. (2020). Protein condensates as aging Maxwell fluids. Science, 370(6522), 1317-1323. doi:10.1126/science.aaw4951. [PubMan] : Nüske, E., Marini, G., Richter, D., Leng, W., Bogdanova, A., Franzmann, T., Pigino, G., & Alberti, S. (2020). Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells. Biology open, 9(7): bio.046391. doi:10.1242/bio.046391. [PubMan] : Iserman, C., Altamirano, C. D., Jegers, C., Friedrich, U., Zarin, T., Fritsch, A., Mittasch, M., Domingues, A., Hersemann, L., Jahnel, M., Richter, D., Guenther, U.-P., Hentze, M. W., Moses, A. M., Hyman, A., Kramer, G., Kreysing, M., Franzmann, T., & Alberti, S. (2020). Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production. Cell, 181(4), 818-831. doi:10.1016/j.cell.2020.04.009. [PubMan] : Guillén-Boixet, J., Kopach, A., Holehouse, A. S., Wittmann, S., Jahnel, M., Schlüßler, R., Kim, K., Trussina, I., Wang, J., Mateju, D., Poser, I., Maharana, S., Ruer-Gruß, M., Richter, D., Zhang, X., Chang, Y.-T., Guck, J., Honigmann, A., Mahamid, J., Hyman, A., Pappu, R. V., Alberti, S., & Franzmann, T. (2020). RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell, 181(2), 346-361. doi:10.1016/j.cell.2020.03.049. [PubMan] : Mediani, L., Guillén-Boixet, J., Vinet, J., Franzmann, T., Bigi, I., Mateju, D., Carrà, A. D., Morelli, F. F., Tiago, T., Poser, I., Alberti, S., & Carra, S. (2019). Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin. The EMBO journal, 38(15): e101341. doi:10.15252/embj.2018101341. [PubMan] : Franzmann, T., & Alberti, S. (2019). Protein Phase Separation as a Stress Survival Strategy. Cold Spring Harbor perspectives in biology, 11(6): a034058. doi:10.1101/cshperspect.a034058. [PubMan] : Franzmann, T., & Alberti, S. (2019). Protein Phase Separation as a Stress Survival Strategy. Cold Spring Harbor perspectives in biology, 11(6): a034058. doi:10.1101/cshperspect.a034058. [PubMan] : Franzmann, T., & Alberti, S. (2019). Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior. The Journal of biological chemistry, 294(18), 7128-7136. doi:10.1074/jbc.TM118.001190. [PubMan] : Ivanov, I., Lira, R. B., Tang, T.-Y.-D., Franzmann, T., Klosin, A., da Silva, L. C., Hyman, A., Landfester, K., Lipowsky, R., Sundmacher, K., & Dimova, R. (2019). Directed Growth of Biomimetic Microcompartments. Advanced Biosystems, 3(6): 1800314. doi:10.1002/adbi.201800314. [PubMan] : Ivanov, I., Lira, R. d., Tang, T.-Y.-D., Franzmann, T., Klosin, A., Caire da Silva, L., Hyman, A. A., Landfester, K., Lipowsky, R., Sundmacher, K., & Dimova, R. (2019). Directed Growth of Biomimetic Microcompartments. Advanced Biosystems, 3(6): 1800314. doi:10.1002/adbi.201800314. [PubMan] : Franzmann, T., & Alberti, S. (2019). Protein Phase Separation as a Stress Survival Strategy. Cold Spring Harbor Perspectives in Biology, 11(6). doi:10.1101/cshperspect.a034058. [PubMan] : Ivanov, I., Lira, R. d., Tang, T.-Y.-D., Franzmann, T., Klosin, A., Caire da Silva, L., Hyman, A., Landfester, K., Lipowsky, R., Sundmacher, K., & Dimova, R. (2019). Directed Growth of Biomimetic Microcompartments. Advanced Biosystems, 3(6): 1800314. doi:10.1002/adbi.201800314. [PubMan] : Alberti, S., Saha, S., Woodruff, J., Franzmann, T., Wang, J., & Hyman, A. (2018). A User's Guide for Phase Separation Assays with Purified Proteins. Journal of molecular biology, 430(23), 4806-4820. doi:10.1016/j.jmb.2018.06.038. [PubMan] : Kroschwald, S., Munder, M., Maharana, S., Franzmann, T., Richter, D., Ruer, M., Hyman, A., & Alberti, S. (2018). Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery. Cell reports, 23(11), 3327-3339. doi:10.1016/j.celrep.2018.05.041. [PubMan] : Maharana, S., Wang, J., Papadopoulos, D., Richter, D., Pozniakovsky, A. I., Poser, I., Bickle, M., Rizk, S., Guillén-Boixet, J., Franzmann, T., Jahnel, M., Marrone, L., Chang, Y.-T., Sterneckert, J., Tomancak, P., Hyman, A., & Alberti, S. (2018). RNA buffers the phase separation behavior of prion-like RNA binding proteins. Science (New York, N.Y.), 360(6391), 918-921. doi:10.1126/science.aar7366. [PubMan] : Franzmann, T., Jahnel, M., Pozniakovsky, A. I., Mahamid, J., Holehouse, A. S., Nüske, E., Richter, D., Baumeister, W., Grill, S. W., Pappu, R. V., Hyman, A. A., & Alberti, S. (2018). Phase separation of a yeast prion protein promotes cellular fitness. Science (New York, N.Y.), 359(6371): eaao5654. doi:10.1126/science.aao5654. [PubMan] : Maharana, S., Wang, J., Papadopoulos, D., Richter, D., Pozniakovsky, A. I., Poser, I., Bickle, M., Rizk, S., Guillén-Boixet, J., Franzmann, T., Jahnel, M., Marrone, L., Chang, Y.-T., Sterneckert, J., Tomancak, P., Hyman, A., & Alberti, S. (2018). RNA buffers the phase separation behavior of prion-like RNA binding proteins. Science (New York, N.Y.), 360(6391), 918-921. doi:10.1126/science.aar7366. [PubMan]