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  Vaccine against carbapenem-resistant klebsiella pneumoniae

Seeberger, P. H., Pereira, C. L., Xiao, G., Khan, N., & Chakkumkal, A.(2016). Vaccine against carbapenem-resistant klebsiella pneumoniae.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-038D-9 Version Permalink: https://hdl.handle.net/21.11116/0000-0001-007A-6
Genre: Patent

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 Creators:
Seeberger, Peter H.1, Author           
Pereira, Claney Lebev2, Author           
Xiao, Guozhi3, Author           
Khan, Naeem3, Author           
Chakkumkal, Anish4, Author           
Affiliations:
1Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2040285              
2Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863308              
3Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863286              
4Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863299              

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 Abstract: The present invention relates to synthetic saccharides of general fornnula (I): V*−[Ux+2−Ux+ 1−Ux]n−V−O−L−NH2 that are related to carbapenem-resistant Kliebsella pneumoniae capsular polysaccharide and conjugates thereof. Said conjugates and pharmaceutical composition containing said conjugates are useful for prevention and/or treatment of diseases associated with carbapenem-resistant Klebsiella pneumoniae. Furthermore, the synthetic saccharides of general formula (I): V*−[Ux+2−Ux+1−Ux]n−V−O−L−NH2 are useful as marker in immunological assays for detection of antibodies against carbapenem-resistant Klebsiella pneumoniae bacteria.

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 Dates: 2016-03-292016-10-06
 Publication Status: Published online
 Pages: -
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 Rev. Type: -
 Identifiers: Patent Application Nr.: WO2016EP56832
Patent Publication Nr.: WO2016156338 A1
Patent Nr.: EP3274358
Patent Nr.: US2018078630
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