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  Generation and characterization of an Advillin-Cre driver mouse line

Zurborg, S., Piszczek, A., Martinez, C., Hublitz, P., Al Banchaabouchi, M., Moreira, P., et al. (2011). Generation and characterization of an Advillin-Cre driver mouse line. Molecular Pain, 7: 66. doi:10.1186/1744-8069-7-66.

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 Creators:
Zurborg, Sandra1, Author           
Piszczek, Agnieszka1, Author
Martinez, Conception1, Author
Hublitz, Philip 1, Author
Al Banchaabouchi, Mumna 1, Author
Moreira, Pedro 1, Author
Perlas, Emerald1, Author
Heppenstall, Paul A.1, Author
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1Mouse Biology Unit, European Molecular Biology Laboratory (EMBL), Monterotondo, Italy, ou_persistent22              

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 Abstract: Progress in the somatosensory field has been restricted by the limited number of genetic tools available to study gene function in peripheral sensory neurons. Here we generated a Cre-driver mouse line that expresses Cre-recombinase from the locus of the sensory neuron specific gene Advillin. These mice displayed almost exclusive Cre-mediated recombination in all peripheral sensory neurons. As such, the Advillin-Cre-driver line will be a powerful tool for targeting peripheral neurons in future investigations.

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Language(s): eng - English
 Dates: 2011-04-212011-09-112011-09-11
 Publication Status: Published online
 Pages: -
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 Rev. Type: -
 Identifiers: DOI: 10.1186/1744-8069-7-66
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Title: Molecular Pain
Source Genre: Journal
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Publ. Info: London, United Kingdom : BioMed Central
Pages: - Volume / Issue: 7 Sequence Number: 66 Start / End Page: - Identifier: ISSN: 1744-8069
CoNE: https://pure.mpg.de/cone/journals/resource/1744-8069