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  17 O T1/T2* tissue-relaxation rates with anatomical contrast in the rat brain at 16.4 T

Wiesner, H., Balla, D., Pohmann, R., Chen, W., Ugurbil, K., & Uludag, K. (2009). 17 O T1/T2* tissue-relaxation rates with anatomical contrast in the rat brain at 16.4 T. In 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009).

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Wiesner, HM1, 2, Author           
Balla, DZ1, 2, Author           
Pohmann, R1, 2, Author           
Chen , W, Author
Ugurbil, K, Author
Uludag, K1, 2, Author           
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: The direct NMR detection of 17O benefits particularly from higher field strengths and is a promising tool in the study of cerebral oxygen metabolism. The aim of this study was to acquire anatomical MRS images of H2O17 at natural abundance concentration in the rat head at 16.4 T. Intra-cortical contrast and differences in tissue-specific relaxation of brain and muscle tissue were found, enabling optimizations in contrast and sensitivity. Based on these results implications on the spatial specificity of oxygen consumption (CMRO2) measurements using 17O2-enriched gas are discussed.

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 Dates: 2009-04
 Publication Status: Published online
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 Identifiers: BibTex Citekey: 5742
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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Place of Event: Honolulu, HI, USA
Start-/End Date: 2009-04-18 - 2009-04-24

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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 354 Start / End Page: - Identifier: -