ausblenden:
Schlagwörter:
acylcyanation; α-amino nitriles; multicomponent reactions; organocatalysis; acyl cyanides
Zusammenfassung:
Different aldehydes and amines react with acyl cyanides in the presence of a catalytic amount of the Schreiner thiourea catalyst to give the corresponding N-acyl amino nitriles in high yields. The scope of the reaction is broad and both aromatic and aliphatic aldehydes and amines can readily be used.
