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  Nanoscopy of filamentous actin in cortical dendrites of a living mouse.

Willig, K. I., Steffens, H., Gregor, C., Herholt, A., Rossner, M. J., & Hell, S. W. (2014). Nanoscopy of filamentous actin in cortical dendrites of a living mouse. Biophysical Journal, 106(1), L01-L03. doi:10.1016/j.bpj.2013.11.1119.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-F4F3-A Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-CDF5-3
Genre: Journal Article

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 Creators:
Willig, K. I.1, Author              
Steffens, H.1, Author              
Gregor, C., Author
Herholt, A., Author
Rossner, M. J., Author
Hell, S. W.1, Author              
Affiliations:
1Department of NanoBiophotonics, MPI for biophysical chemistry, Max Planck Society, ou_578627              

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 Abstract: We demonstrate superresolution fluorescence microscopy (nanoscopy) of protein distributions in a mammalian brain in vivo. Stimulated emission depletion microscopy reveals the morphology of the filamentous actin in dendritic spines down to 40 μm in the molecular layer of the visual cortex of an anesthetized mouse. Consecutive recordings at 43–70 nm resolution reveal dynamical changes in spine morphology.

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Language(s): eng - English
 Dates: 2014-01-07
 Publication Status: Published in print
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.bpj.2013.11.1119
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Title: Biophysical Journal
Source Genre: Journal
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Pages: - Volume / Issue: 106 (1) Sequence Number: - Start / End Page: L01 - L03 Identifier: -