日本語
 
Help Privacy Policy ポリシー/免責事項
  詳細検索ブラウズ

アイテム詳細

  Resolving anisotropic distributions of correlated vibrational motion in protein hydration water

Heyden, M. (2014). Resolving anisotropic distributions of correlated vibrational motion in protein hydration water. The Journal of Chemical Physics, 141(22), 22D509/1-22D509/10. doi:10.1063/1.4896073.

Item is

基本情報

表示: 非表示:
資料種別: 学術論文

ファイル

表示: ファイル

関連URL

表示:

作成者

表示:
非表示:
 作成者:
Heyden, Matthias1, 著者           
所属:
1Research Group Heyden, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1950292              

内容説明

表示:
非表示:
キーワード: -
 要旨: In this study, we analyze correlations of vibrational motion on the surface of a small globular protein and in its hydration shell. In contrast to single particle hydration water dynamics, which are perturbed by interactions with the protein solute only in the first few hydration layers, we find that correlated, collective motions extend into the surrounding solvent on a 10 Å length scale, specifically at far-infrared frequencies below 100 cm−1. As a function of frequency, we analyze the distribution of correlated longitudinal motions in the three-dimensional environment of the protein solute, as well as in the vicinity of different protein-water interfaces. An anisotropic distribution of these correlations is observed, which is related to specific protein-water vibrations and interactions at the interfaces, as well as flexibilities of solvent exposed sites. Our results show that coupling of protein and water dynamics leaves a three-dimensional imprint in the collective dynamics of its hydration shell, and we discuss potential implications for biomolecular function, e.g., molecular recognition and binding, and the dynamical coupling of proteins to their native solvation environment.

資料詳細

表示:
非表示:
言語: eng - English
 日付: 2014-07-112014-09-082014-10-032014-12-14
 出版の状態: 出版
 ページ: 10
 出版情報: -
 目次: -
 査読: 査読あり
 識別子(DOI, ISBNなど): DOI: 10.1063/1.4896073
 学位: -

関連イベント

表示:

訴訟

表示:

Project information

表示:

出版物 1

表示:
非表示:
出版物名: The Journal of Chemical Physics
  その他 : J. Chem. Phys.
種別: 学術雑誌
 著者・編者:
所属:
出版社, 出版地: Woodbury, N.Y. : American Institute of Physics
ページ: 10 巻号: 141 (22) 通巻号: - 開始・終了ページ: 22D509/1 - 22D509/10 識別子(ISBN, ISSN, DOIなど): ISSN: 0021-9606
CoNE: https://pure.mpg.de/cone/journals/resource/954922836226