ausblenden:
Schlagwörter:
-
Zusammenfassung:
The present invention provides an oligosaccharide-protein
conjugate comprising an oligosaccharide, in particular synthetic oligosaccharide,
derived from the repeating unit of the Clostridium difjicile glycopolymer
PS-II and a protein carrier. More specifically, the oligosaccharide is
the hexasaccharide having the following formula (I) wherein R is a linker or
spacer group. In a specific embodiment of the invention, R is (CH2)nNHz,
with n being an integer from 2 to 50. The present invention also provides the
use of said oligosaccharide and said oligosaccharide-protein conjugate for
the treatment or prevention of a disease caused by the pathogen Clostridium
difjicile. In still further aspects, the present invention also provides a favourable
method for preparing said oligosaccharide and said oligosaccharide-protein
conjugate.
