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  Eliminating Pinned Spiral Waves in Cardiac Monolayer by Far Field Pacing

Shajahan, T. K., Krinski, V., Knyazeva, S., & Luther, S. (2014). Eliminating Pinned Spiral Waves in Cardiac Monolayer by Far Field Pacing. In 8th Conference of the ESGCO (pp. 151-152). IEEE.

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 Urheber:
Shajahan, T. K.1, Autor           
Krinski, Valentin1, Autor           
Knyazeva, Svetlana1, Autor           
Luther, Stefan1, Autor           
Affiliations:
1Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063288              

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Schlagwörter: EXCITABLE MEDIUM; ELECTRIC-FIELD; MUSCLE
 Zusammenfassung: Fibrillation in the heart often consists of multiple spiral waves of electrical activation in cardiac tissue. To terminate these multiple waves, recently proposed Low Energy Antifibrillation Pacing (LEAP) uses a series of low energy pulses. This achieves an energy reduction of about 80% in animal experiments. To understand the mechanism of LEAP we study the interaction of electric pulses with pinned spiral waves in monolayers of cardiac cells. Optical mapping and controlled placing of heterogeneities allow us to observe the activation dynamics in these monolayers during field pulsing. We show that a pinned wave can be terminated by a series of pulses when one of the pulses falls in the vulnerable window of the pinned spiral.

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Sprache(n): eng - English
 Datum: 2014
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 708935
 Art des Abschluß: -

Veranstaltung

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Titel: 8th Conference of the European-Study-Group-on-Cardiovascular-Oscillations (ESGCO)
Veranstaltungsort: Trento, Italy
Start-/Enddatum: 2014-05-25 - 2014-05-28

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Titel: 8th Conference of the ESGCO
Genre der Quelle: Konferenzband
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: IEEE
Seiten: - Band / Heft: - Artikelnummer: - Start- / Endseite: 151 - 152 Identifikator: ISBN: 978-1-4799-3969-5