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  Aptamer-based affinity labeling of proteins

Vinkenborg, J. L., Mayer, G., & Famulok, M. (2012). Aptamer-based affinity labeling of proteins. Angewandte Chemie (International ed.in English), 51(36), 9176-80. doi:10.1002/anie.201204174.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-63FF-D Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-6400-0
Genre: Journal Article

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 Creators:
Vinkenborg, J. L., Author
Mayer, G., Author
Famulok, M.1, Author
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1External Organizations, ou_persistent22              

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Free keywords: Affinity Labels/*chemistry Aptamers, Nucleotide/*chemistry Cell Line, Tumor Humans Proteins/*chemistry/metabolism Proto-Oncogene Proteins c-met/chemistry/metabolism SELEX Aptamer Technique Ultraviolet Rays
 Abstract: A most able label: Labeled aptamers can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes can be enriched in vitro, from a cellular lysate and from the surface of living cells, opening new ways to study aptamer interactions in biological contexts.

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 Dates: 2012
 Publication Status: Published in print
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 Identifiers: Other: 22865679
DOI: 10.1002/anie.201204174
ISSN: 1521-3773 (Electronic)
ISSN: 1433-7851 (Linking)
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Title: Angewandte Chemie (International ed.in English)
  Alternative Title : Angew. Chem. Int. Ed. Engl.
Source Genre: Journal
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Pages: - Volume / Issue: 51 (36) Sequence Number: - Start / End Page: 9176 - 80 Identifier: -