English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  High-resolution myocardial T1 mapping using single-shot inversion-recovery fast low-angle shot MRI with radial undersampling and iterative reconstruction.

Wang, X., Joseph, A. A., Kalentev, O., Merboldt, K. D., Voit, D., Roeloffs, V. B., et al. (2016). High-resolution myocardial T1 mapping using single-shot inversion-recovery fast low-angle shot MRI with radial undersampling and iterative reconstruction. British Journal of Radiology, 89(1068): 20160255. doi:10.1259/bjr.20160255.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-ACB4-1 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-29EB-2
Genre: Journal Article

Files

show Files
hide Files
:
2354767.pdf (Publisher version), 3MB
Name:
2354767.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
:
2354767-Suppl.avi (Supplementary material), 546KB
Name:
2354767-Suppl.avi
Description:
-
Visibility:
Public
MIME-Type / Checksum:
video/x-msvideo / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Wang, X.1, Author              
Joseph, A. A.1, Author              
Kalentev, O.1, Author              
Merboldt, K. D.1, Author              
Voit, D.1, Author              
Roeloffs, V. B.1, Author              
van Zalk, M.1, Author              
Frahm, J.1, Author              
Affiliations:
1Biomedical NMR Research GmbH, MPI for Biophysical Chemistry, Max Planck Society, ou_578634              

Content

show
hide
Free keywords: -
 Abstract: To develop a novel method for rapid myocardial T1 mapping at high spatial resolution. METHODS: The proposed strategy represents a single-shot inversion-recovery (IR) experiment triggered to early diastole during a brief breathhold. The measurement combines an adiabatic inversion pulse with a real-time readout by highly undersampled radial FLASH, iterative image reconstruction and T1 fitting with automatic deletion of systolic frames. The method was implemented on a 3 T MRI system using a GPU-equipped bypass computer for online application. Validations employed a T1 reference phantom including analyses at simulated heart rates from 40 to 100 bpm. In vivo applications involved myocardial T1 mapping in short-axis views of healthy young volunteers. RESULTS: At 1 mm in-plane resolution and 6 mm section thickness, the IR measurement could be shortened to 3 s without compromising T1 quantitation. Phantom studies demonstrated T1 accuracy and high precision for values ranging from 300 to 1500 ms and up to a heart rate of 100 bpm. Similar results were obtained in vivo yielding septal T1 values of 1246 ± 24 ms (base), 1256 ± 33 ms (mid-ventricular) and 1288 ± 30 ms (apex), respectively (mean ± SD, n=6). CONCLUSION: Diastolic myocardial T1 mapping with use of single-shot inversion-recovery FLASH offers high spatial resolution, T1 accuracy and precision, practical robustness and speed. Advances in knowledge: The proposed method will be beneficial for clinical applications relying on native and post-contrast T1 quantitation.

Details

show
hide
Language(s): eng - English
 Dates: 2016-11-182016-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1259/bjr.20160255
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: British Journal of Radiology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: 8 Volume / Issue: 89 (1068) Sequence Number: 20160255 Start / End Page: - Identifier: -