English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse
  1. Start / 
  2. View item

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  How to control cyclic nucleotide signaling by light

Jansen, V., Jikeli, J., & Wachten, D. (2017). How to control cyclic nucleotide signaling by light. Current Opinion in Biotechnology, 48, 15-20. doi:10.1016/j.copbio.2017.02.014.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-AF54-7 Version Permalink: https://hdl.handle.net/21.11116/0000-0008-87EA-8
Genre: Journal Article

Files

show Files
hide Files
:
Jansen_How_2017.pdf (Publisher version), 2MB
 
File Permalink:
-
Name:
Jansen_How_2017.pdf
Description:
-
OA-Status:
Visibility:
Private
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Locator:
http://www.sciencedirect.com/science/article/pii/S0958166916302968 (Publisher version)
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Jansen, Vera1, Author           
Jikeli, Jan1, Author           
Wachten, Dagmar2, Author           
Affiliations:
1Department of Molecular Sensory Systems, Center of Advanced European Studies and Research (caesar), Max Planck Society, ou_2173679              
2Max Planck Research Group Molecular Physiology, Center of Advanced European Studies and Research (caesar), Max Planck Society, ou_2173682              

Content

show
hide
Free keywords: -
 Abstract: Highlights
- Optogenetics controls cyclic nucleotide signaling with spatio-temporal resolution.
- Genetic-engineering creates new tools by combining photosensory and effector domains.
- Optogenetic control of cyclic nucleotide signaling controls physiological functions.
Abstract
Optogenetics allows to non-invasively manipulate cellular functions with spatio-temporal precision by combining genetic engineering with the control of protein function by light. Since the discovery of channelrhodopsin has pioneered the field, the optogenetic toolkit has been ever expanding and allows now not only to control neuronal activity by light, but rather a multitude of other cellular functions. One important application that has been established in recent years is the light-dependent control of second messenger signaling. The optogenetic toolkit now allows to control cyclic nucleotide-dependent signaling by light in vitro and in vivo.

Details

show
hide
Language(s): eng - English
 Dates: 2017-03-102017-12
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.copbio.2017.02.014
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Current Opinion in Biotechnology
  Abbreviation : Curr Opin Biotechnol
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Elsevier Current Trends
Pages: - Volume / Issue: 48 Sequence Number: - Start / End Page: 15 - 20 Identifier: ISSN: 0958-1669
CoNE: https://pure.mpg.de/cone/journals/resource/954925577053