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  A morphometric analysis of synaptic vesicle distributions.

Fox, G. (1988). A morphometric analysis of synaptic vesicle distributions. Brain Research, 475(1), 103-117. doi:10.1016/0006-8993(88)90203-X.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-2B87-E Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-2B89-A
Genre: Journal Article

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 Creators:
Fox, G.1, Author              
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1Research Group of Electron Microscopy, MPI for biophysical chemistry, Max Planck Society, ou_578563              

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Free keywords: Synaptic terminal; Synaptic vesicle; Vesicle size; Vesicle density; Vesicle distribution; Particle distribution; Morphometric analysis; Electronic organ
 Abstract: Synaptic vesicle populations have been morphometrically analyzed for size and density. Populations composed of a single size class of vesicles are represented by normal (Gaussian) or positive (log-normal)skew histograms. Populations with multiple size classes generate negative (left) skew distributions. Fixatives containing aldehydes differentially affect these distribution patterns but vesicles are able to withstand tonic effects over a wide range. Reader bias' contribute the most error in the data-collecting process. But despite this, the sizing of vesicle populations can be accomplished with great accuracy. Vesicle density computations, on the other hand, vary over a wide range and are of less value for comparative purposes.

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Language(s): eng - English
 Dates: 1988-12-13
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/0006-8993(88)90203-X
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Title: Brain Research
Source Genre: Journal
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Publ. Info: -
Pages: - Volume / Issue: 475 (1) Sequence Number: - Start / End Page: 103 - 117 Identifier: -