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  Gonadal development and gametogenesis in the hypogonadal mouse are restored by gene transfer

Mason, A. J., Pitts, A. L., Nikolics, K., Szonyi, E., Szonyi, J. N., Seeburg, P. H., et al. (1987). Gonadal development and gametogenesis in the hypogonadal mouse are restored by gene transfer. Annals of the New York Academy of Sciences, 513, 16-26. doi:10.1111/j.1749-6632.1987.tb24995.x.

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Genre: Journal Article
Alternative Title : Testicular development and spermatogenesis in the hypogonadal mouse are restored by gene therapy

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AnnNYAS_513_1987_16.pdf (Any fulltext), 4MB
 
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 Creators:
Mason, Anthony J., Author
Pitts, A. L., Author
Nikolics, Károly, Author
Szonyi, E., Author
Szonyi, J. N., Author
Seeburg, Peter H.1, Author           
Stewart, T. A., Author
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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 Abstract: These results describe controlled regulation of a mammalian neural gene in transgenic mice. Analysis of truncated GnRH-GAP genes in transgenic mice will enable us to define the DNA sequences responsible for this control. Furthermore, by separate mutation of the GnRH and GAP coding sequences we will be able to determine the relative importance of these two peptides in the development and maintenance of reproductive function.

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Language(s): eng - English
 Dates: 1987-12
 Publication Status: Issued
 Pages: 11
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 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: Annals of the New York Academy of Sciences
  Other : Ann. N.Y. Acad. Sci.
Source Genre: Journal
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Publ. Info: New York : New York Academy of Sciences
Pages: - Volume / Issue: 513 Sequence Number: - Start / End Page: 16 - 26 Identifier: ISSN: 0077-8923
CoNE: https://pure.mpg.de/cone/journals/resource/954926958894_2