morFeus: a web-based program to detect remotely conserved orthologs using 
symmetrical best hits and orthology network scoring.

Wagner, Ines; Volkmer, Michael; Sharan, Malvika; Villaveces, Jose M; Oswald, Felix; Surendranath, Vineeth; Habermann, Bianca

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morFeus: a web-based program to detect remotely conserved orthologs using symmetrical best hits and orthology network scoring.

Wagner, I., Volkmer, M., Sharan, M., Villaveces, J. M., Oswald, F., Surendranath, V., et al. (2014). morFeus: a web-based program to detect remotely conserved orthologs using symmetrical best hits and orthology network scoring. BMC Bioinformatics, 15: 263.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0001-05BC-6 Version Permalink: https://hdl.handle.net/21.11116/0000-0001-05BD-5

Genre: Journal Article

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Wagner, Ines¹, Author
Volkmer, Michael¹, Author
Sharan, Malvika, Author
Villaveces, Jose M, Author
Oswald, Felix¹, Author
Surendranath, Vineeth¹, Author
Habermann, Bianca¹, Author

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1Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692

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Abstract: Searching the orthologs of a given protein or DNA sequence is one of the most important and most commonly used Bioinformatics methods in Biology. Programs like BLAST or the orthology search engine Inparanoid can be used to find orthologs when the similarity between two sequences is sufficiently high. They however fail when the level of conservation is low. The detection of remotely conserved proteins oftentimes involves sophisticated manual intervention that is difficult to automate.

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Dates: Date issued: 2014

Publication Status: Issued

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Identifiers: eDoc: 705738
Other: 5874

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Title: BMC Bioinformatics

Source Genre: Journal

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Pages: - Volume / Issue: 15 Sequence Number: 263 Start / End Page: - Identifier: -