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  The Angular Dependence of the Gradient Echo and Spin Echo Bold Signal Induced by Cortical Micro- and Macro- Vasculature

Báez-Yáñez, M., Tsai, P., Kleinfeld, D., & Scheffler, K. (2018). The Angular Dependence of the Gradient Echo and Spin Echo Bold Signal Induced by Cortical Micro- and Macro- Vasculature. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0001-7D6F-8 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-936D-F
Genre: Poster

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Báez-Yáñez, M1, 2, Author              
Tsai, PS, Author
Kleinfeld, D, Author
Scheffler, K1, 2, Author              
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: In recent investigations, the angular dependence of the BOLD signal with respect to the main magnetic field has been shown by Monte Carlo simulations and experimental approaches. This orientation dependence is often attributed to the contribution of large vessels (cortical surface and penetrating arteries/veins). However, the ability to resolve cortical layers and columns depends ultimately on the contribution of the MR signal generated by the capillary bed. In this work, we studied the MR signal attenuation generated by a vascular network model that was acquired from the parietal cortex of mice using a two-photon laser imaging techniques. We separately investigated the impact of macrovessels (>5 µm in diameter) and microvessels (< 5 µm in diameter) on the BOLD effect.

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 Dates: 2018-06
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: BaezYanezTKS2018
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 5454 Start / End Page: - Identifier: -