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  Multiple Interleaved Mode Saturation (MIMOSA) for B1+ inhomogeneity mitigation in chemical exchange saturation transfer

Liebert, A., Zaiss, M., Gumbrecht, R., Schmitt, B., Linz, P., Laun, F., et al. (2018). Multiple Interleaved Mode Saturation (MIMOSA) for B1+ inhomogeneity mitigation in chemical exchange saturation transfer. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

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Liebert, A, Author
Zaiss, M1, 2, Author           
Gumbrecht, R, Author
Schmitt, B, Author
Linz, P, Author
Laun, FB, Author
Uder, M, Author
Nagel, AM, Author
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1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Due to high sensitivity to B1+-inhomogeneities, Chemical Exchange Saturation Transfer MRI requires a correction or mitigation of the B1+-inhomogeneity at ultra-high magnetic field strengths (B0 ≥ 7 Tesla). A novel approach for mitigation of B1+-inhomogeneity effects that affects the saturation process is presented. The method employs two interleaved excitation modes during the saturation pulse train. Simulations show a decrease of the relative difference of the MTRRex metric caused by B1+ inhomogeneity. This “Multiple Interleaved Mode Saturation” scheme leads to improved homogeneity in both, phantom and in vivo measurements at 7 Tesla.

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 Dates: 2018-06
 Publication Status: Issued
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 Identifiers: BibTex Citekey: LiebertZGSLLUN2018
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 2230 Start / End Page: - Identifier: -