Cyclization of natural products

O'Connor, Sarah E.

doi:10.1038/nchembio1006-511

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Cyclization of natural products

O'Connor, S. E. (2006). Cyclization of natural products. Nature Chemical Biology, 2(10), 511-512. doi:10.1038/nchembio1006-511.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-A530-D Version Permalink: https://hdl.handle.net/21.11116/0000-0009-3D6F-8

Genre: Journal Article

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O'Connor, Sarah E.¹, Author

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Free keywords: THIOESTERASE DOMAIN; POLYKETIDE; SYNTHASEBiochemistry & Molecular Biology;

Abstract: Enzymatic cyclization of the linear polyketide chain to form a macrolactone is a key step in the biosynthesis of type I polyketide natural products. Structural biology and inhibitor design were used to gain insight into the mechanism and specificity of this enzymatic process.

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Language(s): eng - English

Dates: Date issued: 2006

Publication Status: Issued

Pages: 2

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Identifiers: Other: SOC009
DOI: 10.1038/nchembio1006-511

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Title: Nature Chemical Biology

Other : Nat. Chem. Biol.

Source Genre: Journal

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Publ. Info: New York, NY : Nature Pub. Group

Pages: - Volume / Issue: 2 (10) Sequence Number: - Start / End Page: 511 - 512 Identifier: ISSN: 1552-4450
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000021290_1