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Free keywords:
B cell receptor; B cells; DTR; anti-CD20
Abstract:
BReDi mice express a red fluorescent protein together with the diphtheria toxin receptor selectively in Bcells. Bcells can be effectively visualized by red fluorescence and can be efficiently depleted in a highly controlled fashion to study their functional capacity in vivo. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.