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  Ultra high field BOLD measurements combined with simultaneous determination of blood oxygenation and blood volume by optical imaging

Bernard, R., Scheffler, K., & Pohmann, R. (2019). Ultra high field BOLD measurements combined with simultaneous determination of blood oxygenation and blood volume by optical imaging. In ISMRM 27th Annual Meeting & Exhibition.

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 Creators:
Bernard, R1, 2, Author           
Scheffler, K1, 2, Author           
Pohmann, R1, 2, Author           
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: To disentangle the different parameters contributing to the BOLD effect, a combined setup for intrinsic optical imaging and ultra high field fMRI in rats was designed, using a magnetic field compatible, high sensitivity camera and professional optical components. By illumination of the brain surface with light in four different wavelengths, oxygenation and CBV was observed concurrently with fMRI during forepaw stimulation. Simultaneous measurement of those parameters can help to better understand the BOLD effect and to add additional value to both optical imaging and fMRI experiments.

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 Dates: 2019-05
 Publication Status: Published online
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Title: 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019)
Place of Event: Montréal, QC, Canada
Start-/End Date: 2019-05-11 - 2019-05-16

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Title: ISMRM 27th Annual Meeting & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0205 Start / End Page: - Identifier: -