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  Diffusion Weighted Images in the Cat Visual Cortex at 9.4 T Reveal Extravascular Related ADC Decreases During Activation

Yacoub, E., Uludag, K., Ugurbil, K., & Harel, N. (2007). Diffusion Weighted Images in the Cat Visual Cortex at 9.4 T Reveal Extravascular Related ADC Decreases During Activation. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

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Yacoub, E, Author
Uludag, K1, 2, Author              
Ugurbil, K, Author
Harel, N, Author
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: It has been previously suggested that there is a decrease in the water diffusion coefficient during neuronal activation and that diffusion MRI can reveal these changes. Furthermore, such changes have been attributed to transient cell swelling, caused either by a shrinking of the extracellular space or by some intracellular neuronal process which precedes any vascular response. Evidence for these processes can be investigated via high resolution diffusion sensitized functional magnetic resonance imaging. Here in this work, we use the cat visual cortex model at 9.4 Tesla to investigate diffusion weighted fMRI signal changes using very high b-values.

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 Dates: 2007-05
 Publication Status: Published in print
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
Start-/End Date: 2007-05-19 - 2007-05-25

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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1620 Start / End Page: 331 Identifier: -