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  Localization analysis of TMS effects during motor cortex stimulation

Weise, K., Numssen, O., Thielscher, A., Hartwigsen, G., & Knösche, T. R. (2018). Localization analysis of TMS effects during motor cortex stimulation. Poster presented at 24th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Singapore.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0004-A97F-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0005-5F22-B
Genre: Poster

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 Creators:
Weise, Konstantin1, 2, Author              
Numssen, Ole3, Author              
Thielscher, A.4, Author
Hartwigsen, Gesa3, Author              
Knösche, Thomas R.1, Author              
Affiliations:
1Methods and Development Unit - MEG and Cortical Networks, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205650              
2Technische Universität Ilmenau, ou_persistent22              
3Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3025665              
4Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_persistent22              

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Free keywords: TMS; MEP; FEM; GPC; Congruence factor; Modeling; Simulation
 Abstract: Transcranial magnetic stimulation (TMS) allows for non-invasive electromagnetic stimulation of the cortex. However, its exact neurophysiological mechanisms remain elusive, leading to considerable variation in observed effects [1]. Depending on stimulation intensity and target, the stimulation can directly lead to observable effects, such as motor re- sponses. Although head modeling allows for a prediction of the induced electric field in the head [2], the stimulated areas may be extended and do not uni- quely identify the location of the effect cause. Here, we present a novel method that employs biophysical forward modeling (Fig. 2) and stimulation with variable coil positions and orientations, in order to exactly localize the neural populations that are causally linked to motor evoked potentials (MEP).

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 Dates: 2018-06
 Publication Status: Not specified
 Pages: -
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 Rev. Type: -
 Identifiers: -
 Degree: -

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Title: 24th Annual Meeting of the Organization for Human Brain Mapping (OHBM)
Place of Event: Singapore
Start-/End Date: 2018-06-17 - 2018-06-21

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