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  On the follicular pathway of percutaneous uptake of nanoparticles: Ion microscopy and autoradiography studies

Lekki, J., Stachura, Z., Dabroś, W., Stachura, J., Menzel, F., Reinert, T., et al. (2007). On the follicular pathway of percutaneous uptake of nanoparticles: Ion microscopy and autoradiography studies. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 260(1), 174-177. doi:10.1016/j.nimb.2007.02.021.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0004-CED9-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0004-CEDA-F
Genre: Journal Article

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 Creators:
Lekki, J.1, Author
Stachura, Z.1, Author
Dabroś, W.1, Author
Stachura, J.1, Author
Menzel, F.1, Author
Reinert, Tilo1, Author              
Butz, T.1, Author
Pallon, J.1, Author
Gontier, E.1, Author
Ynsa, M. D.1, Author
Moretto, P.1, Author
Kertesz, Z.1, Author
Szikszai, Z.1, Author
Kiss, A. Z.1, Author
Affiliations:
1External Organizations, ou_persistent22              

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Free keywords: Titanium dioxide; Nanoparticles; Skin penetration; Ion microprobe; Autoradiography
 Abstract: We report on the visualization of the penetration of sunscreen formulations containing TiO2 nanoparticles (about 20 nm primary particle size) into hair follicles of both human and porcine skin using the complementary methods of ion microscopy (PIXE, RBS, STIM) and autoradiography. Particles were found as deep as approx. 400 μm in the follicle, obviously introduced mechanically rather than by a diffusive process. No particles were observed in vital tissue nor in sebaceous glands.

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Language(s): eng - English
 Dates: 2007-02-142007-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.nimb.2007.02.021
BibTex Citekey: Lekki:2007
 Degree: -

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Title: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
  Abbreviation : NIM B
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier B.V.
Pages: - Volume / Issue: 260 (1) Sequence Number: - Start / End Page: 174 - 177 Identifier: ISSN: 0168-583X
CoNE: https://pure.mpg.de/cone/journals/resource/954925484704