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  Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus.

Pfaff, E., Mussgay, M., Böhm, H., Schulz, G. E., & Schaller, H. (1982). Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus. EMBO Journal, 1(7), 869-874. doi:10.1002/j.1460-2075.1982.tb01262.x.

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EMBOJ_1_1982_869.pdf (Any fulltext), 2MB
 
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Pfaff, E., Author
Mussgay, M., Author
Böhm, H.O., Author
Schulz, Georg E.1, Author           
Schaller , H., Author
Affiliations:
1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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Free keywords: FMD; virus/synthetic peptide: vaccine/peptide antigens
 Abstract: A major antibody combining site on foot and mouth disease virus (FMDV) serotype O1K has been identified in a predicted surface helix of viral protein 1 (VP1) between amino acid residues 144 and 159. A hexadecapeptide covering this sequence elicits high titers of antibodies that specifically recognize and neutralize FMDV. The high quality of the immune response is attributed to a particularly stable conformation of the antigenic amino acid sequence, which is most likely an alpha‐helix.

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Language(s): eng - English
 Dates: 1982-07-121982-07-01
 Publication Status: Issued
 Pages: 6
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: EMBO Journal
  Other : EMBO J.
Source Genre: Journal
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Publ. Info: Nature Publishing Group
Pages: - Volume / Issue: 1 (7) Sequence Number: - Start / End Page: 869 - 874 Identifier: ISSN: 0261-4189
CoNE: https://pure.mpg.de/cone/journals/resource/954925497061