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  Rolling ES cells down the Waddington landscape with Oct4 and Sox2

Iovino, N., & Cavalli, G. (2011). Rolling ES cells down the Waddington landscape with Oct4 and Sox2. Cell, 145, 815-817. doi:10.1016/j.cell.2011.05.027.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0006-0787-A Version Permalink: https://hdl.handle.net/21.11116/0000-0006-0788-9
Genre: Journal Article

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Iovino et al..pdf (Publisher version), 215KB
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 Creators:
Iovino, Nicola1, Author           
Cavalli, Giacomo2, Author
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1Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243643              
2External Organizations, ou_persistent22              

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 Abstract: Embryonic stem cell (ESC) pluripotency is maintained by core transcriptional circuits whereby critical factors sustain their own expression while preventing the expression of genes required for differentiation. Thomson et al. (2011) now show that two core components of the pluripotency circuit, Oct4 and Sox2, are also critical for germ layer fate choice.

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Language(s): eng - English
 Dates: 2011-06-10
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.cell.2011.05.027
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Title: Cell
Source Genre: Journal
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Publ. Info: Cambridge, Mass. : Cell Press
Pages: - Volume / Issue: 145 Sequence Number: - Start / End Page: 815 - 817 Identifier: ISSN: 0092-8674
CoNE: https://pure.mpg.de/cone/journals/resource/954925463183