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  From pyrazolones to azaindoles : evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

Mostinski, Y., Heynen, G. J. J. E., López-Alberca, M. P., Paul, J., Miksche, S., Radetzki, S., et al. (2020). From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement. Journal of Medicinal Chemistry, 63(23), 14780-14804. doi:10.1021/acs.jmedchem.0c01265.

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Genre: Journal Article

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 Creators:
Mostinski, Yelena, Author
Heynen, Guus J. J. E., Author
López-Alberca, Maria Pascual, Author
Paul, Jerome, Author
Miksche, Sandra, Author
Radetzki, Silke, Author
Schaller, David, Author
Shanina, Elena1, Author              
Seyffarth, Carola, Author
Kolomeets, Yuliya, Author
Ziebart, Nandor, Author
de Schryver, Judith, Author
Oestreich, Sylvia, Author
Neuenschwander, Martin, Author
Roske, Yvette, Author
Heinemann, Udo, Author
Rademacher, Christoph1, Author              
Volkamer, Andrea, Author
von Kries, Jens Peter, Author
Birchmeier, Walter, Author
Nazaré, Marc, Author more..
Affiliations:
1Christoph Rademacher, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863300              

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Free keywords: Cells, Inhibitors, Inhibition, Cancer, Peptides and proteins
 Abstract: -

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Language(s): eng - English
 Dates: 2020-11-192020
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1021/acs.jmedchem.0c01265
BibTex Citekey: doi:10.1021/acs.jmedchem.0c01265
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Title: Journal of Medicinal Chemistry
Source Genre: Journal
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Publ. Info: Washington DC : ACS Publications
Pages: - Volume / Issue: 63 (23) Sequence Number: - Start / End Page: 14780 - 14804 Identifier: ISSN: 0022-2623