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  Photo-tethered molecular beacons for superior light-induction

Klimek, R., Wang, M., McKenney, V. R., Schuman, E. M., & Heckel, A. (2020). Photo-tethered molecular beacons for superior light-induction. Chem Commun (Camb). doi:10.1039/d0cc06704k.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0007-EEE5-B Version Permalink: https://hdl.handle.net/21.11116/0000-0007-EEE6-A
Genre: Journal Article

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https://www.ncbi.nlm.nih.gov/pubmed/33346255 (Any fulltext)
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Klimek, R.1, Author
Wang, M.1, Author
McKenney, V. R.1, Author
Schuman, E. M.1, Author
Heckel, A.1, Author
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1Max Planck Society, ou_persistent13              

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 Abstract: We developed a superior class of light-activatable molecular beacons with photo-tethered loop regions. Two simple modifications and probe cyclisation prevent the molecular beacon from hybridising with the target RNA before light-activation. Full activity of the molecular beacon is elicited upon illumination with 365 nm light.

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 Dates: 2020-12-22
 Publication Status: Issued
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 Identifiers: Other: 33346255
DOI: 10.1039/d0cc06704k
ISSN: 1364-548X (Electronic) 1359-7345 (Linking)
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Title: Chem Commun (Camb)
Source Genre: Journal
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