Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
 
 
DownloadE-Mail
 DetailsÜbersicht
  Luminal Sodium Phosphate Cotransport as the Site of Regulation for Tubular Phosphate Reabsorption: Studies with Isolated Membrane Vesicles

Murer, H., Stoll, R., Evers, C., Kinne, R., Bonjour, J.-P., & Fleisch, H. (1980). Luminal Sodium Phosphate Cotransport as the Site of Regulation for Tubular Phosphate Reabsorption: Studies with Isolated Membrane Vesicles. In Current Topics in Membranes and Transport (pp. 275-281). Academic Press Inc. doi:10.1016/S0070-2161(08)60287-7.

Item is

 

einblenden: alle ausblenden: alle

Basisdaten

einblenden: ausblenden:
Datensatz-Permalink: https://hdl.handle.net/21.11116/0000-0008-53AE-7 Versions-Permalink: https://hdl.handle.net/21.11116/0000-0008-53AF-6
Genre: Buchkapitel

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Murer, Heini1, Autor           
Stoll, Reinhard1, Autor           
Evers, Carla1, Autor           
Kinne, Rolf1, Autor           
Bonjour, Jean-Philippe2, Autor
Fleisch, Herbert2, Autor
Affiliations:
1Department of Physiology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068297              
2Department of Palhophysiology, University of Berne, Berne, Switzerland, ou_persistent22              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 Zusammenfassung: Publisher Summary: This chapter describes experiments in which alterations in proximal tubular inorganic phosphate (Pi) reabsorption were achieved in vivo by various means and sodium-dependent transport of Pi across the luminal membrane was analyzed in vitro with isolated membrane vesicles. Transport of Pi across cells consists of the following: (1) uphill influx across the brush border membrane via a sodium–Pi cotransport system driven by the gradients of sodium and Pi across the brush border membrane and (2) efflux of Pi at the contraluminal cell side driven by the electrochemical potential difference for Pi. The administration of parathyroid hormone slowed down the initial uptake phase and also reduced the intravesicular accumulation of Pi; however, this hormone did not provoke an alteration in the uptake of Pi in the absence of sodium. In the different situations tested earlier, a significant change was observed only in the sodium-dependent transport of Pi and not in the sodium-dependent transport of glucose. A close relationship exists between the estimate of the tubular capacity for Pi reabsorption of the whole kidney and the Pi uptake in the brush border vesicles measured under various conditions. Such a correlation strongly suggests that the translocation step across the brush border membrane is of primary importance in the regulation of the transport of Pi along the renal tubule.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2008-05-301980-12
 Publikationsstatus: Erschienen
 Seiten: 7
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1016/S0070-2161(08)60287-7
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Current Topics in Membranes and Transport
  Untertitel : Cellular Mechanisms of Renal Tubular Ion Transport
Genre der Quelle: Reihe
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Academic Press Inc.
Seiten: - Band / Heft: 13 Artikelnummer: - Start- / Endseite: 275 - 281 Identifikator: ISSN: 0070-2161