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  Ten millennia of hepatitis B virus evolution

Kocher, A., Papac, L., Barquera Lozano, R. J., Key, F. M., Spyrou, M. A., Hübler, R., Rohrlach, A. B., Aron, F., Stahl, R., Wissgott, A., van Bömmel, F., Pfefferkorn, M., Mittnik, A., Villalba-Mouco, V., Neumann, G., Rivollat, M., Loosdrecht, M. S. v. d., Majander, K., Tukhbatova, R. I., Musralina, L., Ghalichi, A., Penske, S. E., Sabin, S., Michel, M., Gretzinger, J., Nelson, E. A., Ferraz da Silva, T., Nägele, K., Parker, C. E., Keller, M., Guevara, E., Feldman, M., Eisenmann, S., Skourtanioti, E., Giffin, K., Gnecchi Ruscone, G. A., Friederich, S., Schimmenti, V., Khartanovich, V., Karapetian, M. K., Chaplygin, M. S., Kufterin, V. V., Khokhlov, A. A., Chizhevsky, A. A., Stashenkov, D. A., Kochkina, A. F., Tejedor-Rodríguez, C., de Lagrán, Í.-G.-M., Arcusa-Magallón, H., Garrido-Pena, R., Royo-Guillén, J. I., Novácek, J., Rottier, S., Kacki, S., Saintot, S., Kaverzneva, E., Belinskiy, A. B., Velemínský, P., Limburský, P., Kostka, M., Loe, L., Popescu, E., Clarke, R., Lyons, A., Mortimer, R., Sajantila, A., de Armas, Y. C., Godoy, S. T. H., Hernández-Zaragoza, D. I., Pearson, J., Binder, D., Lefranc, P., Kantorovich, A. R., Maslov, V. E., Lai, L., Zoledziewska, M., Beckett, J. F., Langová, M., Danielisová, A., Ingman, T., Atiénzar, G. G., de Ibáñez, M. P. M., Romero, A., Sperduti, A., Beckett, S., Salter, S. J., Zilivinskaya, E. D., Vasilev, D. V., von Heyking, K., Burger, R. L., Salazar, L. C., Amkreutz, L., Navruzbekov, M., Rosenstock, E., Alonso-Fernández, C., Slavchev, V., Kalmykov, A. A., Atabiev, B. C., Batieva, E., Calmet, M. A., Llamas, B., Schultz, M., Krauß, R., Jiménez-Echevarría, J., Francken, M., Shnaider, S., de Knijff, P., Altena, E., de Vijver, K. V., Fehren-Schmitz, L., Tung, T. A., Lösch, S., Dobrovolskaya, M., Makarov, N., Read, C., Twest, M. V., Sagona, C., Ramsl, P. C., Akar, M., Yener, K. A., Ballestero, E. C., Cucca, F., Mazzarello, V., Utrilla, P., Rademaker, K., Fernández-Domínguez, E., Baird, D., Semal, P., Márquez-Morfín, L., Roksandic, M., Steiner, H., Salazar-García, D. C., Shishlina, N., Erdal, Y. S., Hallgren, F., Boyadzhiev, Y., Boyadzhiev, K., Küßner, M., Sayer, D., Onkamo, P., Skeates, R., Rojo-Guerra, M., Buzhilova, A., Khussainova, E., Djansugurova, L. B., Beisenov, A. Z., Samashev, Z., Massy, K., Mannino, M., Moiseyev, V., Mannermaa, K., Balanovsky, O., Deguilloux, M.-F., Reinhold, S., Hansen, S., Kitov, E. P., Dobeš, M., Ernée, M., Meller, H., Alt, K. W., Prüfer, K., Warinner, C. G., Schiffels, S., Stockhammer, P. W., Bos, K. I., Posth, C., Herbig, A., Haak, W., Krause, J., & Kühnert, D. (2021). Ten millennia of hepatitis B virus evolution. Science, 374(6564):, pp. 182-188. doi:10.1126/science.abi5658.

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基本情報

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アイテムのパーマリンク: https://hdl.handle.net/21.11116/0000-0009-6D08-5 版のパーマリンク: https://hdl.handle.net/21.11116/0000-0009-6D09-4
資料種別: 学術論文

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shh3071.pdf (出版社版), 3MB
 
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pdf. - available in institutes network. - (last seen: Nov. 2021)
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Data S1 to S4 (付録資料)
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zip. - available in institutes network. - (last seen: Nov. 2021)
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pdf. - available in institutes network. - (last seen: Nov. 2021)
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作成者

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 作成者:
Kocher, Arthur1, 著者           
Papac, Luka2, 著者           
Barquera Lozano, Rodrigo José2, 著者           
Key, Felix Michael2, 著者           
Spyrou, Maria A.2, 著者           
Hübler, Ron2, 著者           
Rohrlach, Adam Ben2, 著者           
Aron, Franziska2, 著者           
Stahl, Raphaela2, 著者           
Wissgott, Antje2, 著者           
van Bömmel, Florian, 著者
Pfefferkorn, Maria, 著者
Mittnik, Alissa2, 著者           
Villalba-Mouco, Vanessa2, 著者           
Neumann, Gunnar2, 著者           
Rivollat, Maïté2, 著者           
Loosdrecht, Marieke Sophia van de2, 著者           
Majander, Kerttu2, 著者           
Tukhbatova, Rezeda I.2, 著者           
Musralina, Lyazzat2, 著者           
全て表示
所属:
1tide, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2591691              
2Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              

内容説明

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キーワード: -
 要旨: Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.

資料詳細

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言語: eng - English
 日付: 2021-10-082021-10
 出版の状態: 出版
 ページ: 8
 出版情報: -
 目次: - The MRCA of all known HBV lineages
- HBV circulated widely in western Eurasia as early as 10 ka
- A replacement of HBV diversity occurred with the Neolithic transition in Europe
- The collapse of WENBA HBV during the 2nd millennium BCE
- Recent reemergence of the WENBA HBV lineage
- Conclusions
 査読: 査読あり
 識別子(DOI, ISBNなど): DOI: 10.1126/science.abi5658
その他: shh3071
 学位: -

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Project information

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Project name : PALEoRIDER
Grant ID : 771234
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)
Project name : CoDisEASe
Grant ID : 805268
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)

出版物 1

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出版物名: Science
  省略形 : Science
種別: 学術雑誌
 著者・編者:
所属:
出版社, 出版地: Washington, D.C. : American Association for the Advancement of Science
ページ: - 巻号: 374 (6564) 通巻号: abi5658 開始・終了ページ: 182 - 188 識別子(ISBN, ISSN, DOIなど): ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1