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  Ten millennia of hepatitis B virus evolution

Kocher, A., Papac, L., Barquera Lozano, R. J., Key, F. M., Spyrou, M. A., Hübler, R., et al. (2021). Ten millennia of hepatitis B virus evolution. Science, 374(6564): abi5658, pp. 182-188. doi:10.1126/science.abi5658.

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 Creators:
Kocher, Arthur1, Author           
Papac, Luka2, Author           
Barquera Lozano, Rodrigo José2, Author           
Key, Felix Michael2, Author           
Spyrou, Maria A.2, Author           
Hübler, Ron2, Author           
Rohrlach, Adam Ben2, Author           
Aron, Franziska2, Author           
Stahl, Raphaela2, Author           
Wissgott, Antje2, Author           
van Bömmel, Florian, Author
Pfefferkorn, Maria, Author
Mittnik, Alissa2, Author           
Villalba-Mouco, Vanessa2, Author           
Neumann, Gunnar2, Author           
Rivollat, Maïté2, Author           
Loosdrecht, Marieke Sophia van de2, Author           
Majander, Kerttu2, Author           
Tukhbatova, Rezeda I.2, Author           
Musralina, Lyazzat2, Author           
Ghalichi, Ayshin2, Author           Penske, Sandra Ellen2, Author           Sabin, Susanna2, Author           Michel, Megan2, Author           Gretzinger, Joscha2, Author           Nelson, Elizabeth A.2, Author           Ferraz da Silva, Tiago2, Author           Nägele, Kathrin2, Author           Parker, Cody Edward2, Author           Keller, Marcel2, Author           Guevara, Evelyn2, Author           Feldman, Michal2, Author           Eisenmann, Stefanie2, Author           Skourtanioti, Eirini2, Author           Giffin, Karen2, Author           Gnecchi Ruscone, Guido Alberto2, Author           Friederich, Susanne, AuthorSchimmenti, Vittoria, AuthorKhartanovich, Valery, AuthorKarapetian, Marina K., AuthorChaplygin, Mikhail S., AuthorKufterin, Vladimir V., AuthorKhokhlov, Aleksandr A., AuthorChizhevsky, Andrey A., AuthorStashenkov, Dmitry A., AuthorKochkina, Anna F., AuthorTejedor-Rodríguez, Cristina, Authorde Lagrán, Íñigo García-Martínez, AuthorArcusa-Magallón, Héctor, AuthorGarrido-Pena, Rafael, AuthorRoyo-Guillén, José Ignacio, AuthorNovácek, Jan, AuthorRottier, Stéphane, AuthorKacki, Sacha, AuthorSaintot, Sylvie, AuthorKaverzneva, Elena, AuthorBelinskiy, Andrej B., AuthorVelemínský, Petr, AuthorLimburský, Petr, AuthorKostka, Michal, AuthorLoe, Louise, AuthorPopescu, Elizabeth, AuthorClarke, Rachel, AuthorLyons, Alice, AuthorMortimer, Richard, AuthorSajantila, Antti, Authorde Armas, Yadira Chinique, AuthorGodoy, Silvia Teresita Hernandez, AuthorHernández-Zaragoza, Diana I., AuthorPearson, Jessica, AuthorBinder, Didier, AuthorLefranc, Philippe, AuthorKantorovich, Anatoly R., AuthorMaslov, Vladimir E., AuthorLai, Luca, AuthorZoledziewska, Magdalena, AuthorBeckett, Jessica F., AuthorLangová, Michaela, AuthorDanielisová, Alžbeta, AuthorIngman, Tara, AuthorAtiénzar, Gabriel García, Authorde Ibáñez, Maria Paz Miguel, AuthorRomero, Alejandro, AuthorSperduti, Alessandra, AuthorBeckett, Sophie, AuthorSalter, Susannah J., AuthorZilivinskaya, Emma D., AuthorVasilev, Dmitry V., Authorvon Heyking, Kristin, AuthorBurger, Richard L., AuthorSalazar, Lucy C., AuthorAmkreutz, Luc, AuthorNavruzbekov, Masnav, AuthorRosenstock, Eva, AuthorAlonso-Fernández, Carmen, AuthorSlavchev, Vladimir, AuthorKalmykov, Alexey A., AuthorAtabiev, Biaslan Ch., AuthorBatieva, Elena, AuthorCalmet, Micaela Alvarez, AuthorLlamas, Bastien, AuthorSchultz, Michael, AuthorKrauß, Raiko, AuthorJiménez-Echevarría, Javier, AuthorFrancken, Michael, AuthorShnaider, Svetlana, Authorde Knijff, Peter, AuthorAltena, Eveline, Authorde Vijver, Katrien Van, AuthorFehren-Schmitz, Lars, AuthorTung, Tiffiny A., AuthorLösch, Sandra, AuthorDobrovolskaya, Maria, AuthorMakarov, Nikolaj, AuthorRead, Chris, AuthorTwest, Melanie Van, AuthorSagona, Claudia, AuthorRamsl, Peter C., AuthorAkar, Murat, AuthorYener, K. Aslihan, AuthorBallestero, Eduardo Carmona, AuthorCucca, Francesco, AuthorMazzarello, Vittorio, AuthorUtrilla, Pilar, AuthorRademaker, Kurt, AuthorFernández-Domínguez, Eva, AuthorBaird, Douglas, AuthorSemal, Patrick, AuthorMárquez-Morfín, Lourdes, AuthorRoksandic, Mirjana, AuthorSteiner, Hubert, AuthorSalazar-García, Domingo Carlos, AuthorShishlina, Natalia, AuthorErdal, Yilmaz Selim, AuthorHallgren, Fredrik, AuthorBoyadzhiev, Yavor, AuthorBoyadzhiev, Kamen, AuthorKüßner, Mario, AuthorSayer, Duncan, AuthorOnkamo, Päivi, AuthorSkeates, Robin, AuthorRojo-Guerra, Manuel, AuthorBuzhilova, Alexandra, AuthorKhussainova, Elmira, AuthorDjansugurova, Leyla B., AuthorBeisenov, Arman Z., AuthorSamashev, Zainolla, AuthorMassy, Ken, AuthorMannino, Marcello, AuthorMoiseyev, Vyacheslav, AuthorMannermaa, Kristiina, AuthorBalanovsky, Oleg, AuthorDeguilloux, Marie-France, AuthorReinhold, Sabine, AuthorHansen, Svend, AuthorKitov, Egor P., AuthorDobeš, Miroslav, AuthorErnée, Michal, AuthorMeller, Harald, AuthorAlt, Kurt W., AuthorPrüfer, Kay2, Author           Warinner, Christina G.2, Author           Schiffels, Stephan2, Author           Stockhammer, Philipp W.2, Author           Bos, Kirsten I.2, Author           Posth, Cosimo2, Author           Herbig, Alexander2, Author           Haak, Wolfgang2, Author           Krause, Johannes2, Author           Kühnert, Denise1, 2, Author            more..
Affiliations:
1tide, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2591691              
2Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              

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 Abstract: Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.

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Language(s): eng - English
 Dates: 2021-10-082021-10
 Publication Status: Issued
 Pages: 8
 Publishing info: -
 Table of Contents: - The MRCA of all known HBV lineages
- HBV circulated widely in western Eurasia as early as 10 ka
- A replacement of HBV diversity occurred with the Neolithic transition in Europe
- The collapse of WENBA HBV during the 2nd millennium BCE
- Recent reemergence of the WENBA HBV lineage
- Conclusions
 Rev. Type: Peer
 Identifiers: DOI: 10.1126/science.abi5658
Other: shh3071
 Degree: -

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Project name : PALEoRIDER
Grant ID : 771234
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)
Project name : CoDisEASe
Grant ID : 805268
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)

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Title: Science
  Abbreviation : Science
Source Genre: Journal
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Publ. Info: Washington, D.C. : American Association for the Advancement of Science
Pages: - Volume / Issue: 374 (6564) Sequence Number: abi5658 Start / End Page: 182 - 188 Identifier: ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1